Peoples Perceptions of Forms of Renal Replacement Therapy

NCT04427800 | Completed

• 1 other identifier: 005JA
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic kidney disease (CKD) causes symptoms and potential loss of independence. These effects are increased as the disease progress to endstage renal disease (ESRD), particularly when external intervention (i.e. dialysis) is used to keep these individuals alive. The combined effect of ESRD and its treatment has a significant impact on an individual's life, potentially causing reduced employment time, reduced social time and increased anxiety/stress. The purpose of this study is to investigate the impact that CKD/ESRD have on an individual's life. Specifically, this study is focused on giving an insight into the psychosocial impact that CKD/ESRD and different forms of renal replacement therapy have upon these individuals.

Conditions

Chronic Kidney Diseases

Outcome Measures

Primary Outcomes (1)

• Thematic analysis of qualitative interview exploring the experiences of renal disease and renal replacement therapy in adults with advanced chronic kidney disease and end-stage renal disease

  Qualitative interviews to explore the above experiences

  Day 1

Study Arms (6)

CKD G4

Chronic kidney disease stage (G4). (eGFR \< 30 mL/min/1.73m2)

CKD G5

Chronic kidney disease stage (G5). (eGFR \< 15 mL/min/1.73m2) with imminent initiation of RRT

ESRD on ICHD

End stage renal disease on in centre haemodialysis

ESRD on HHD

End stage renal disease on home haemodialysis

ESRD on PD

End stage renal disease on peritoneal dialysis

Post-transplant

Participants post-transplant

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults with advanced CKD/ESRD (eGFR \< 30 mL/min/1.73m2 ) will be recruited into this study. Persons falling into six distinct categories will be approached: 1. CKD G4 2. CKD G5 with imminent initiation of RRT 3. ESRD on ICHD 4. ESRD on HHD 5. ESRD on PD 6. Post-transplant

You may qualify if:

• Aged 18 years or older Willing and able to undertake the interview process Able to give informed consent

You may not qualify if:

• Age \< 18 years Does not provide written informed consent Any neurological/psychiatric diagnoses Lack of fluency in English Individuals who have commenced RRT within three months of the study start date Transplant patients being seen in clinic more than once every fortnight

Sponsors & Collaborators

• University of Portsmouth: lead
• Portsmouth Hospitals NHS Trust: collaborator
• University of Reading: collaborator

Study Sites (1)

School of Sport Health and Exercise Science

Portsmouth, Outside the United States Or Canada, PO1 2ER, United Kingdom

Location

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior Lecturer in Physical Activity, Exercise and Health

Study Record Dates

• First Submitted: June 4, 2020
• First Posted: June 11, 2020
• Study Start: October 4, 2019
• Primary Completion: November 24, 2020
• Study Completion: November 24, 2020
• Last Updated: September 28, 2021

Record last verified: 2021-09

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)