Longitudinal Follow-up of Male Soccer Players Prone to Developing CAM Hip Deformity

NCT04418596 | Completed DMC

• 1 other identifier: S62916
• Study Type: observational
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

Femoroacetabular impingement (FAI) is a clinical problem in which abnormal contact occurs between the thighbone and the hip socket. In intensive, mostly still young, male athletes, this problem seems to be related to a bony deformity on the head of this thighbone, a so-called CAM. FAI itself gives rise to pain symptoms, but in time can even lead to premature osteoarthritis. However, the cause of a CAM deformity itself, nor how FAI then arises, is insufficiently known. In view of FAI prevention and its better treatment, this project thus tries to better understand the underlying mechanisms. For this purpose, we will combine detailed biomechanical evaluations of specific movement patterns with advanced medical imaging and state of the art clinical evaluations to longitudinally follow up a group with a known high risk of developing a CAM deformity, being young male elite soccer players. Findings within this study will be additionally compared with similar analyses performed in patients with FAI. This research aims to thus form a basis to define novel (sports-specific) training schemes for the prevention of FAI, but also to define the actual treatment and rehabilitation plans in more patient-specific and a better-informed way.

Conditions

Femoro Acetabular Impingement; CAM

Outcome Measures

Primary Outcomes (1)

• The formation of CAM deformity on the anterior head-neck junction of the femur

  Detected using alpha angle on MRI/ Dunn's View x-ray

  two years post baseline measurements

Study Arms (2)

Elite Soccer Players

Adolescent male aged 12-16 years old elite athletes that are recruited from special sport school in Leuven-Belgium and play football at a high level.

Radiation: bi-planer radiography (EOS), Conventional radiography (Hip+pelvis)

Recreational Soccer players (control)

Adolescent male aged 12-16 years old recruited from ordinary school in Flanders Belgium that play soccer or any other sport recreationally with no high intensity training

Radiation: bi-planer radiography (EOS), Conventional radiography (Hip+pelvis)

Interventions

bi-planer radiography (EOS), Conventional radiography (Hip+pelvis) RADIATION

low dose radiation medical imaging to visualise the hip joint and lumbo-pelvic complex specifically.

Also known as: Clinical Screening, Motion Analysis

Elite Soccer Players; Recreational Soccer players (control)

Eligibility Criteria

• Age: 12 Years - 17 Years
• Gender Eligibility Details: Genetic component of being a male is required .
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Adolescent healthy males that are starting the final age of skeletal maturity(12-18 years of age). The 2 groups of the study are separated principally on the frequency and intensity of their athletic training.

You may qualify if:

• For the the Elite Group: Playing soccer at high level and training for more that 10 hours a week
• For the Control group: Playing soccer or any other sport recreationally for a less than 5 hours a week

You may not qualify if:

• No prior history of major trauma or injury to the lower limbs and spine
• No prior history of neurological conditions that can effect movement and mobility

Sponsors & Collaborators

• Universitaire Ziekenhuizen KU Leuven: lead
• Johnson & Johnson: collaborator

Study Sites (1)

University of Leuven Hospitals

Leuven, Flanders, 3000, Belgium

Location

MeSH Terms

Conditions

Femoracetabular Impingement

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Stijn Ghijselings, M.D.

  Universitaire Ziekenhuizen KU Leuven

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 3, 2020
• First Posted: June 5, 2020
• Study Start: September 1, 2019
• Primary Completion: May 15, 2024
• Study Completion: May 15, 2024
• Last Updated: April 11, 2025

Record last verified: 2025-04

Locations

BE (1)