Analysis of Radiographic and Kinematic Features in FAI Patients

NCT05867069 | Completed

• 1 other identifier: S2021436
• Study Type: observational
• Target: 93
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to describe the radiographic and kinematic features in patients with femoroacetabular impingement syndrome (FAI). The main questions it aims to answer are:

• Is structural knee abnormalities associated with knee pain symptoms in FAI patients?
• Does FAI patients with knee pain demonstrate unique kinematic characteristics？ Participants will receive routine preoperative radiographic examinations, which include ipsilateral knee MRI for the purpose of femoral version measurement. Participants will also receive markerless motion capture analysis. Researchers will compare preoperative radiographic and kinematic features based on knee pain status, which is routinely collected as part of clinical investigation procedures.

Conditions

Femoro Acetabular Impingement

Outcome Measures

Primary Outcomes (4)

• Preoperative radiographic cartilage defect of ipsilateral knee

  On the same day of admission, patients receive routine preoperative MRI examination of the hip and ipsilateral knee for femoral version measurement. Radiographs of ipsilateral knee MRI are evaluated for the presence of structural knee abnormality. Radiographic signs suggesting cartilage defect of the patella, femur and the tibial plateau are collected.

  Knee MRI radiographs are evaluated at baseline.

• Preoperative radiographic meniscal tear of ipsilateral knee

  On the same day of admission, patients receive routine preoperative MRI examination of the hip and ipsilateral knee for femoral version measurement. Radiographs of ipsilateral knee MRI are evaluated for the presence of structural knee abnormality. Radiographic signs suggesting lateral or medial meniscal tears are collected.

  Knee MRI radiographs are evaluated at baseline.

• Preoperative radiographic ligament ruptures of ipsilateral knee

  On the same day of admission, patients receive routine preoperative MRI examination of the hip and ipsilateral knee for femoral version measurement. Radiographs of ipsilateral knee MRI are evaluated for the presence of structural knee abnormality. Radiographic signs suggesting ACL tears, PCL tears or collateral ligament ruptures are collected.

  Knee MRI radiographs are evaluated at baseline.

• Foot progression angle during normal gait

  The next day after admission, patients undergo markerless motion capture evaluation after informed consents are obtained. Movements for motion capture include normal gait, stepping in place, single-leg stance, double-leg squat and forward lunge. Each movement is repeated 2 times. The entire data collection process for each patient takes approximately 120 seconds. Foot progression angle during gait are assessed with MATLAB in a retrospective fashion after completion of patient recruitment.

  Motion capture data are assessed at baseline.

Study Arms (2)

Ipsilateral knee pain group

Those FAI patients presenting with preoperative ipsilateral knee pain.

No ipsilateral knee pain group

Those FAI patients presenting without preoperative ipsilateral knee pain.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Consecutive patients diagnosed with FAI and admitted into the sports medicine department at Peking university third hospital for hip arthroscopic surgery by a single surgeon.

You may qualify if:

• (1) diagnosed with FAI based on clinical and radiographical findings;
• (2) failed conservative treatment for at least 6 months and indicated for surgical treatment;
• (3) received routine preoperative hip and ipsilateral knee MRI.

You may not qualify if:

• (1) history of fracture or surgery of hip and knee;
• (2) avascular necrosis;
• (3) Legg-Calve-Perthes disease;
• (4) Ehlers-Danlos syndrome;
• (5) pigmented villonodular synovitis (PVNS);
• (6) osteoid osteoma (OO);
• (7) synovial chondromatosis;
• (8) severe hip osteoarthritis (OA) with Tönnis grade \> 1;
• (9) developmental dysplasia of hip (DDH)

Sponsors & Collaborators

• Peking University Third Hospital: lead

Study Sites (1)

Peking University Third Hospital

Beijing, 100191, China

Location

MeSH Terms

Conditions

Femoracetabular Impingement

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Yan Xu, M.D.

  Peking University Third Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 25, 2023
• First Posted: May 19, 2023
• Study Start: September 1, 2021
• Primary Completion: February 28, 2022
• Study Completion: February 28, 2022
• Last Updated: May 19, 2023

Record last verified: 2023-04

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)