Pregnant Women for Malaria Surveillance
MiPMon
Pregnant Women as a Sentinel Group for Malaria Surveillance in an Era of Changing Malaria Transmission
1 other identifier
observational
16,958
0 countries
N/A
Brief Summary
Close monitoring of malaria in pregnancy can help to quickly identify changes in malaria burden and related adverse outcomes, especially in areas embarking in malaria elimination activities. The easy access of pregnant women through antenatal clinics, combined with the potential of pregnancy-specific serology to assess cumulative exposure to malaria, can provide the basis for new sentinel surveillance methods. Such an approach has the potential to guide clinical practice and the choice of malaria control/preventive tools adapted to areas of different transmission intensity, as well as to generate sensitive metrics of transmission during malaria elimination activities.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2016
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 31, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
October 31, 2019
CompletedFirst Submitted
Initial submission to the registry
May 28, 2020
CompletedFirst Posted
Study publicly available on registry
June 2, 2020
CompletedJune 9, 2020
May 1, 2020
3 years
May 28, 2020
June 4, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number of pregnant women with a P. falciparum infection
P. falciparum detected by qPCR
3 years
Secondary Outcomes (2)
Number of pregnant women with maternal anemia
3 years
Number of pregnant women delivering a newborn with low birthweight
3 years
Study Arms (3)
Manhiça
Pregnant women attending the Manhiça District Hospital
Ilha Josina
Pregnant women attending the Ilha Josina Health Center
Magude
Pregnant women attending the Magude Health Center
Interventions
Eligibility Criteria
Pregnant women attending three health centers in areas of Maputo Province with different levels of malaria transmission (Manhiça District Hospital \[Manhiça District\], Ilha Josina Health Center \[Manhiça District\] and Magude Health Center \[Magude District\])
You may qualify if:
- Pregnant women attending their first routine ANCs or pregnant women seen at the moment of delivery or pregnant women with signs/symptoms of malaria (axillary temperature ≥ 37.5°C, referred history of fever in the last 24 hours, pallor, arthromyalgias, headache and/or history of convulsions)
- Being equal or older than 16 years
- Being from the study area
You may not qualify if:
- Unwillingness to participate in the study or to have samples obtained
- Not being from the study area.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Biospecimen
Dried blood spots Plasma and PBMCS from a random selection of study participants
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 28, 2020
First Posted
June 2, 2020
Study Start
November 1, 2016
Primary Completion
October 31, 2019
Study Completion
October 31, 2019
Last Updated
June 9, 2020
Record last verified: 2020-05