Impact of Chronic Kidney Disease on Postural Stability in Children

NCT04411927 | Completed

• 1 other identifier: children with CKD
• Study Type: observational
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Chronic kidney disease is associated with comorbid conditions that result in physical impairments. Objectives: Investigate the impact of chronic kidney disease (CKD) on postural stability in children compared with age matched typically developing children using Human Assessment Computer (HUMAC) balance system. Design: An observational design (cross-sectional study). Settings: The assessment procedures were conducted at the Nephrology Unit, Zagazig University Hospitals. Participants: Seventy-five children, age ranged from 8 to 15 years represented three groups of equal numbers; control group (typically developed), non-dialysis (stage 3 and 4) and hemodialysis group. Outcome measures: The HUMAC balance system was used to assess the limits of stability, center of pressure and sensory organization and balance.

Conditions

Chronic Kidney Diseases

Keywords

Balance; Chronic kidney disease; HUMAC balance system; Postural stability

Outcome Measures

Primary Outcomes (3)

• limits of stability test

  it was measured by the HUMAC. higher scores indicate good balance

  from January 2018 to January 2020

• center of pressure (COP) test

  It was measured by the HUMAC balance system. COP is represented by 1. path length higher scores indicate poor balance 2. stability score with higher results indicate good balance

  from January 2018 to January 2020

• Clinical Test of Sensory Organization and Balance

  it was measured by the HUMAc balance system to represent the ability of the child to keep balance while standing on firm and solid surfaces alternatively with eyes open and then eyes closed

  from January 2018 to January 2020

Study Arms (3)

control group

this group included 25 typically developed children

Other: assessment of postural stability

on-heamodialysis group

this group included children with CKD on-heamodialysis treatment

Other: assessment of postural stability

non-dialysis group

this group included children with CKD who don't require dialysis

Other: assessment of postural stability

Interventions

assessment of postural stability OTHER

assessment of postural stability

control group; non-dialysis group; on-heamodialysis group

Eligibility Criteria

• Age: 8 Years - 15 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Fifty eligible volunteer children with CKD were recruited from Nephrology Unit, Zagazig University Hospitals to be enrolled in this study and allocated into either hemodialysis (on hemodialysis) or non-dialysis group (children at stage 3 and 4).

You may qualify if:

• Medically diagnosed with CKD (regardless of medical history),
• Age ranged from eight to fifteen years,
• Both genders

You may not qualify if:

• Participants were excluded if they had:
• Communication problems such as intellectual disability, autism, Down syndrome, or cerebral palsy,
• Significant visual or hearing problems,
• Any neurological and/or musculoskeletal disorders which influence postural stability,
• Chronic cardiovascular or pulmonary disorders.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

faculty of physical therapy, Cairo university

Giza, 12662, Egypt

Location

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Nanees E Mohamed

  Cairo University

  STUDY CHAIR

• Faika S Arab

  zagazieg university, Egypt

  STUDY DIRECTOR

• Nourhan M Baiomy

  Cairo university, Egypt

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Amira Abd-elmonem, assist Prof. Physiacl therapy for pediatric department, faculty of physical therapy , Cairo university

Study Record Dates

• First Submitted: May 18, 2020
• First Posted: June 2, 2020
• Study Start: January 1, 2018
• Primary Completion: January 20, 2020
• Study Completion: January 20, 2020
• Last Updated: November 1, 2022

Record last verified: 2022-10

Locations

EG (1)