Impact of Asthma Exacerbations

NCT04410120 | Unknown

• 1 other identifier: 20038
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to gain a deeper understanding of the impact of asthma attacks on the lives of patients who experience them. This will help us to describe the true extent of the impact of asthma attacks on factors of importance to patients which have not previously been well described, including the psychological, social, financial and emotional burden of asthma attacks. Additionally, it is hoped that detailed questioning regarding features of asthma attacks from a patient perspective will improve our understanding of patient recognition of attacks, consistency of certain features of attacks and patient views regarding preventative strategies for attacks. Patient experiences of asthma attacks are poorly described in previous research. Hence this work is expected to provide useful insights into these experiences which will contribute to improvements in detecting, treating and preventing asthma attacks. The study will consist of a one-off interview lasting about 45 minutes with patients who have recently had asthma attacks. We plan to recruit patients for the study from an outpatient clinic for those who have had a recent attack or from a register of patients who have volunteered for future asthma research studies. The interviews will take place in person at the Respiratory Research Unit at the Nottingham City Hospital or over the telephone depending on patient preference.

Conditions

Asthma Attack

Outcome Measures

Primary Outcomes (1)

• Thematic analysis of interview transcripts using framework approach

  Thematic analysis of interview transcripts using framework approach

  One off 45 minute interview

Study Arms (1)

Asthma with recent (<4/52) asthma attack

Other: Interview

Interventions

Interview OTHER

Semi-structured 45 minute interviews regarding impact of asthma attacks

Asthma with recent (<4/52) asthma attack

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults with previous clinician diagnosis of asthma who have had a recent (≤4 weeks) asthma attack for which they received ≥3 days of systemic corticosteroid treatment

You may qualify if:

• Adults with previous clinician diagnosis of asthma (16 years and above)
• Recent (≤4 weeks) asthma attack for which patient received ≥3 days of systemic corticosteroid treatment

You may not qualify if:

• Anyone under the age of 16 years.
• Anyone unable to speak or understand English.

Sponsors & Collaborators

• University of Nottingham: lead

Study Sites (1)

Nottingham Respiratory Research Unit

Nottingham, Nottinghamshire, NG5 1PB, United Kingdom

Location

Related Publications (1)

• Pradhan A, Jayes L, Bains M, Martin MJ. Patient experience, understanding and self-management of asthma attacks: a qualitative study. J Asthma. 2025 May;62(5):872-880. doi: 10.1080/02770903.2024.2449230. Epub 2025 Jan 10.

  PMID: 39773014 DERIVED

MeSH Terms

Interventions

Interviews as Topic

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 26, 2020
• First Posted: June 1, 2020
• Study Start: September 1, 2020
• Primary Completion: September 1, 2020
• Study Completion: September 1, 2020
• Last Updated: June 1, 2020

Record last verified: 2020-05

Locations

GB (1)