NCT04409574|Unknown
COVID 19 Viral Clearance Among the Infected Healthcare Workers In Assiut University Hospitals
COVID19 Viral Clearance Among the Infected Healthcare Workers In Assiut University Hospitals
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COVID19 Viral Clearance Among the Infected Healthcare Workers In Assiut University Hospitals
Sponsor study identifier
observational
31
0 countries
N/A
Study Start
June 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
March 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
June 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
This work was aimed to determine the time of COVID 19 viral clearance in healthcare workers, assessment of clinical presentation and severity of COVID 19 infection among healthcare workers and discover relation between the time of COVID 19 viral clearance resolution of symptoms
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 28, 2020
Actual (reported)June 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
June 1, 2020
Actual (reported)March 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
June 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
the time of Covid 19 viral clearance in medical healthcare workers and its relation to clinical presentation, severity among and resolution of symptoms.
different relations between different symptoms, investigation results and time of viral clearness
basline
knowledge and practice of infection control measures
baseline
Covid 19 infected healthcare workers in Assiut University Hospital
Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, Ren R, Leung KSM, Lau EHY, Wong JY, Xing X, Xiang N, Wu Y, Li C, Chen Q, Li D, Liu T, Zhao J, Liu M, Tu W, Chen C, Jin L, Yang R, Wang Q, Zhou S, Wang R, Liu H, Luo Y, Liu Y, Shao G, Li H, Tao Z, Yang Y, Deng Z, Liu B, Ma Z, Zhang Y, Shi G, Lam TTY, Wu JT, Gao GF, Cowling BJ, Yang B, Leung GM, Feng Z. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. 2020 Mar 26;382(13):1199-1207. doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29.
Lei J, Kusov Y, Hilgenfeld R. Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein. Antiviral Res. 2018 Jan;149:58-74. doi: 10.1016/j.antiviral.2017.11.001. Epub 2017 Nov 8.
* Complete Blood Count (CBC) by (Pentra 80 Horiba blood counter). * Erythrocyte Sedimentation Rate (ESR) by westergren method. * Liver function , Kidney function tests, triglyceride , LDH, CK, CK-MB Na, K, Mg, Phosphorus, Ca, CRP, Ferritin ) (Dimension RXLautomated blood chemistry analyser). * HCV Ab, HBsAg and HIV Ag-Ab on Abott Architect i1000R * Prothrombin time , concentration, INR and D-Dimerand on sysmex 1500 corona virus investigation: Viral RNA extraction by Qiagen viral RNA extraction large volume: on QiAcube extractor * Coronavirus (Covid -19) genesig Real time PCR assay : on 7500 fast Applied biosystem
First Submitted
May 28, 2020
First Posted
June 1, 2020
Study Start
June 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
March 2021
Evaluation of Activity and Safety of Two Regimens of Low Dose Oral Selinexor in Participants With Moderate or Severe COVID-19
Contact the study team to confirm eligibility.
Wang J, Zhou M, Liu F. Reasons for healthcare workers becoming infected with novel coronavirus disease 2019 (COVID-19) in China. J Hosp Infect. 2020 May;105(1):100-101. doi: 10.1016/j.jhin.2020.03.002. Epub 2020 Mar 6. No abstract available.
Woo PCY, Huang Y, Lau SKP, Yuen KY. Coronavirus genomics and bioinformatics analysis. Viruses. 2010 Aug;2(8):1804-1820. doi: 10.3390/v2081803. Epub 2010 Aug 24.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
June 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
June 4, 2020
Record last verified: 2020-06
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