NCT04402814

Brief Summary

The purpose of this study is to evaluate point of care SARS-Cov2 Virus IgG/IgM rapid test cassette Clungene test and correlate it with the standard method of testing in inpatients who have tested positive or negative for COVID19.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2020

Shorter than P25 for all trials

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 5, 2020

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

May 22, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 27, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2020

Completed
Last Updated

July 27, 2020

Status Verified

July 1, 2020

Enrollment Period

5 months

First QC Date

May 22, 2020

Last Update Submit

July 23, 2020

Conditions

Keywords

CoronavirusCOVID-19ClungeneIgG/IgM antibodies

Outcome Measures

Primary Outcomes (1)

  • IgG/IgM antibodies

    Presence of IgG and/or IgM antibodies

    from date of consent to date of test completion, up to 40 days

Study Arms (2)

Arm A (positive for COVID-19)

One or two samples of your blood that were previously collected for routine care will be obtained from the hospital laboratory and will be tested for the antibodies against COVID-19 virus. * First blood sample obtained: 7 to 12 days following onset of symptoms; and/or * Second blood sample obtained: 12 to 40 days following the onset of symptoms.

Diagnostic Test: Clungene rapid test cassette

Arm B (negative for COVID-19)

One sample of blood that was collected for routine care at any point during hospitalization will be obtained from the hospital laboratory and will be tested for the antibodies.

Diagnostic Test: Clungene rapid test cassette

Interventions

Blood will be tested for the presence of IgG and IgM antibodies using the Clungene rapid test cassette.

Arm A (positive for COVID-19)Arm B (negative for COVID-19)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Hospitalized (or recently discharged) subjects who have been previously tested for COVID-19 with the standard method of testing.

You may qualify if:

  • Received confirmed COVID-19 positive or negative test from Sharp HealthCare's standard method of testing.
  • Age \>/=18 years old.
  • Access to a phone in the hospital room or an electronic device that is capable of receiving phone calls and/or video calls and/or e-mail.
  • Able to read/write/speak English or Spanish fluently.
  • Subjects must have the ability to understand the requirements of the study, provide informed consent, and provide authorization of use and disclosure of personal health information.
  • Hospitalized at the time of consent or recently discharged with leftover blood stored at hospital laboratory

You may not qualify if:

  • Impaired cognitive or decision-making capacity (based on the clinical judgment of the PI or designee)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Fadi A. Haddad MD Inc.

La Mesa, California, 91942, United States

RECRUITING

Sharp Grossmont Hospital

La Mesa, California, 91942, United States

RECRUITING

Sharp Memorial Hosptial

San Diego, California, 92123, United States

RECRUITING

MeSH Terms

Conditions

Coronavirus InfectionsCOVID-19

Condition Hierarchy (Ancestors)

Coronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsVirus DiseasesInfectionsPneumonia, ViralPneumoniaRespiratory Tract InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Fadi Haddad, MD

    Sharp HealthCare

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Infectious Disease Specialist

Study Record Dates

First Submitted

May 22, 2020

First Posted

May 27, 2020

Study Start

May 5, 2020

Primary Completion

October 1, 2020

Study Completion

December 1, 2020

Last Updated

July 27, 2020

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

Locations