Use of suPAR Algorithm for the ED Decision Making
EDsuPAR
Use of Algorithm for Safer and More Efficient Decision Making in the ED
1 other identifier
observational
1,800
1 country
1
Brief Summary
Will the use of a clinical decision algorithm in the ED improve discharge or admission decisions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 11, 2020
CompletedFirst Submitted
Initial submission to the registry
May 20, 2020
CompletedFirst Posted
Study publicly available on registry
May 26, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2021
CompletedFebruary 11, 2022
June 1, 2021
1.1 years
May 20, 2020
January 28, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Discharges
Number of discharges from the ED within 24 hours
30 days
Secondary Outcomes (4)
Admissions
30 days
Length of stay
30 days
Readmissions
1,7 and 30 days
Mortality
30 days
Other Outcomes (1)
Economical savings
30 days
Study Arms (2)
suPAR algoritm control
Control arm (Meilahti hospital): Samples are collected and suPAR measured but no algorithm is implemented.
suPAR algoritm intervention
Intervention arm (Jorvi Hospital). According the algorithm when admitting a patient with suPAR below 3 ng/ml, physician should answer the following question "Are you sure it is the right decision to admit this patient? Please discuss this with a senior physician". If discharging a patient with suPAR above 6 ng/ml, physician should answer the following question "Are you sure it is the right decision to discharge this patient? Please discuss this with a senior physician".
Interventions
All medical patients attending to the ED and who will have blood drawn for routine examination will be part of the study. In patients with low suPAR (green group, suPAR below 3 ng/ml) and in patients with high suPAR (red group, suPAR \> 6 ng/mL) the Intervention will be carried out
Eligibility Criteria
All patients during the study period who signed the consent
You may qualify if:
- All patients above 18 years
- who are having blood taken for biochemical analysis when attending the ED
You may not qualify if:
- Acute medical patients that do not have blood drawn for routine biochemical testing.
- Pregnant
- Under 18 years old
- Terminally ill patients.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Helsinki University Central Hospitallead
- University of Copenhagencollaborator
Study Sites (1)
Department of Emergency Medicine and Services, Helsinki University Hospital and Helsinki University, Helsinki, Finland
Helsinki, Helsinki Usimaa, Finland
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Maaret Castrén, Docent
Professor
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- OTHER
- Target Duration
- 1 Month
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD
Study Record Dates
First Submitted
May 20, 2020
First Posted
May 26, 2020
Study Start
May 11, 2020
Primary Completion
June 1, 2021
Study Completion
June 1, 2021
Last Updated
February 11, 2022
Record last verified: 2021-06
Data Sharing
- IPD Sharing
- Will not share