Root Canal Treatment Outcome in Patients Under Bisphosphonate Therapy
Root Canal Treatment of Compromised Teeth as Alternative Treatment in Patients Under Bisphosphonate Therapy: 60-month Results of a Prospective Clinical Study
1 other identifier
observational
111
0 countries
N/A
Brief Summary
The aim of this study was to evaluate the survival rate and healing time of compromised teeth and seriously compromised teeth that were endodontically treated in patients which received bisphosphonate therapy . Clinical complications, success and survival rate was reported. Mean clinical parameters, clinical symptoms and presence of periapical radilucency were recorded.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2009
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 7, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 15, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
December 15, 2017
CompletedFirst Submitted
Initial submission to the registry
May 20, 2020
CompletedFirst Posted
Study publicly available on registry
May 22, 2020
CompletedMay 27, 2020
May 1, 2020
7.9 years
May 20, 2020
May 23, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
health patients
assessment of periapical index (PAI)
5 years
Secondary Outcomes (1)
Complications
5 years
Study Arms (2)
BPS group
patients under Bisphosphonate therapy for at least 24 months
healthy patients
healthy patients not assuming with no previous Bisphosphonate assumption
Interventions
Root canal treatment using a standard manual k file instrumentation and carrier-based root canal filling technique
Eligibility Criteria
Similar geographic provenience
You may qualify if:
- Patients affected by endodontic disease and able to attend a hygiene recall program
You may not qualify if:
- inability to attend a recall hygien program
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Pirani C, Chersoni S, Montebugnoli L, Prati C. Long-term outcome of non-surgical root canal treatment: a retrospective analysis. Odontology. 2015 May;103(2):185-93. doi: 10.1007/s10266-014-0159-0. Epub 2014 Jun 8.
PMID: 24908421RESULTPrati C, Pirani C, Zamparini F, Gatto MR, Gandolfi MG. A 20-year historical prospective cohort study of root canal treatments. A Multilevel analysis. Int Endod J. 2018 Sep;51(9):955-968. doi: 10.1111/iej.12908. Epub 2018 Mar 7.
PMID: 29432651RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- DDS,MS,PhD
Study Record Dates
First Submitted
May 20, 2020
First Posted
May 22, 2020
Study Start
January 7, 2009
Primary Completion
December 15, 2016
Study Completion
December 15, 2017
Last Updated
May 27, 2020
Record last verified: 2020-05
Data Sharing
- IPD Sharing
- Will not share