Atopic Diseases & Human Papilloma Virus

NCT04397081 | Completed

• 1 other identifier: 494/2019
• Study Type: observational
• Target: 239
• Locations: 1 country
• Sites: 1

Brief Summary

Cervical cancer is an important health problem in women. Human papillomavirus (HPV) is considered the primary etiological agent of cervical cancer worldwide. Cervical cancer screening methods are proved one of the few screening methods that are thought to decrease invasive cancer incidence and mortality. In our country, HPV screening is carried out free of charge by public health to women between the ages of 30-65 aim is to compare HPV screening results between women diagnosed with atopic disease and healthy women without a history of atopy.If HPV is detected more frequently in patients with atopy, it may be recommended to follow more closely in vaccination and screening programs. Therefore, our study was designed to evaluate whether HPV positivity is common in atopic women.

Conditions

Human Papilloma Virus; Atopic Asthma; Atopic Disorders

Keywords

Human papilloma virus,; screening test,; atopic diseases,; asthma,; rhinitis,; urticaria

Outcome Measures

Primary Outcomes (1)

• to compare HPV screening results between women diagnosed with atopic disease and healthy women without a history of atopy.

  comparing HPV test results between groups.

  6 months

Study Arms (2)

Control Group

Control group was defined as healthy patients between the ages of 30-65 without allergic complaints.Patients' height, weight, demographic features (age, marital status, income level), obstetric histories (gravida, parity, mode of delivery), contraception methods and smoking status were noted.

Other: HPV test results

Study group

Study group was defined as patients between the ages of 30-65 with allergic complaints complaints (sneezing, itching,runy nose, respiratory distress) were diagnosed "atopic disease" (allergic asthma, allergic rhinitis, allergic conjunctivitis, chronic urticaria and atopic dermatitis) by same clinician in Immunology and Allergy Department. Patients' height, weight, demographic features (age, marital status, income level), obstetric histories (gravida, parity, mode of delivery), contraception methods and smoking status were noted. Subgroup atopic disease diagnoses, duration of illness, treatments regimes and treatment time of the patients in the study group were also questioned and recorded.

Other: HPV test results

Interventions

HPV test results OTHER

The human papillomavirus (HPV) test detects the presence of the human papillomavirus, a virus that can lead to the development of genital warts, abnormal cervical cells or cervical cancer. The procedure includes taking samples of your cervical cells using a soft brush and a flat scraping device called a spatula. This doesn't hurt, and you may not even feel the sample being taken.

Control Group; Study group

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients between the ages of 30-65 with allergic complaints (sneezing, itching,runy nose, respiratory distress) were diagnosed "atopic disease" (allergic asthma, allergic rhinitis, allergic conjunctivitis, chronic urticaria and atopic dermatitis) by same clinician in Immunology and Allergy Department. Healthy women without allergic complaints applied for routine gynecologic examination occurred control group.

You may qualify if:

• Patients between the ages of 30-65 with allergic complaints (sneezing, itching,runy nose, respiratory distress) diagnosed "atopic disease" (allergic asthma, allergic rhinitis, allergic conjunctivitis, chronic urticaria and atopic dermatitis) by same clinician in Immunology and Allergy Department.
• Patients between the ages of 30-65 without allergic complaints

You may not qualify if:

• Pregnant women
• women who receive immunosuppressive therapy (including chemotherapy and chronic corticosteroid therapy)
• HIV positive women
• women with cancer
• women performed hysterectomy

Sponsors & Collaborators

• Adana Numune Training and Research Hospital: lead

Study Sites (1)

Adana City Education and Research Hospital

Adana, Merkez, 01100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Asthma; Rhinitis; Urticaria

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Respiratory Tract Infections; Infections; Nose Diseases; Otorhinolaryngologic Diseases; Skin Diseases, Vascular; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Gulsum Uysal

  Adana City Education and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor in Obstetrics and Gynecology Department

Study Record Dates

• First Submitted: May 17, 2020
• First Posted: May 21, 2020
• Study Start: August 1, 2019
• Primary Completion: February 29, 2020
• Study Completion: March 30, 2020
• Last Updated: May 26, 2020

Record last verified: 2020-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)