The Effect of Fasting on Serum Osmolarity in Diabetic Patients
The Effect of Ramadan Fasting on Serum Osmolarity in Patients With Type 2 Diabetes
1 other identifier
observational
52
1 country
1
Brief Summary
In Ramadan, Muslims perform a special kind of fasting. Their fasting start with the first lights of the sunrise and end with the sunset. Especially in summer, it is a real challenge, as the time for fasting might be as long as 18 hours, and hot weather might cause severe dehydration. This might be dangerous, especially in patients with diabetes. Serum osmolarity is a good surrogate marker to evaluate the body's fluid content. We aimed to investigate if summertime Ramadan fasting causes further fluid loss in patients with type 2 diabetes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2019
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 15, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 3, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
June 3, 2019
CompletedFirst Submitted
Initial submission to the registry
May 13, 2020
CompletedFirst Posted
Study publicly available on registry
May 19, 2020
CompletedMay 19, 2020
May 1, 2020
19 days
May 13, 2020
May 16, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
To compare the serum osmolarities of patients with type 2 diabetes who are fasting for 17 hours and who are not fasting.
osmolarity is the measure of solute concentration. In our study we used it as a surrogate marker for fluid loss during fasting
1 month
Study Arms (2)
Fasting group
patients with type 2 diabetes who prefer to fast during Ramadan
Non-fasting group
patients with type 2 diabetes who are otherwise healthy and have no contraindications for fasting but prefer not to fast
Interventions
blood samplings will be taken 08:00 am and again 2 hours before breaking the fast
Eligibility Criteria
Outpatients who were attending to the clinics of diabetes in a medical faculty
You may qualify if:
- patients with type 2 diabetes
- will accept to give two different blood samples
- will prefer to fast during Ramadan ( for the intervention group)
- will prefer not to fast during Ramadan ( for the control group)
- have good glycemic control
You may not qualify if:
- if the patients are not eligible for fasting
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
IMU Goztepe Education and Research Hospital
Istanbul, Kadikoy, Turkey (Türkiye)
Related Publications (1)
Keskinler MV, Dincer B, Caklili OT, Oguz A. The effect of Ramadan fasting on serum osmolality in diabetic patients. J Pak Med Assoc. 2023 Apr;73(4):767-770. doi: 10.47391/JPMA.3517.
PMID: 37051980DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mirac Vural Keskinler, MD
IMU Doctoral program
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
May 13, 2020
First Posted
May 19, 2020
Study Start
May 15, 2019
Primary Completion
June 3, 2019
Study Completion
June 3, 2019
Last Updated
May 19, 2020
Record last verified: 2020-05
Data Sharing
- IPD Sharing
- Will not share