Association Between BMI and COVID-19
BMI-SARS-CoV-2
Relationship Between Obesity and Severe Acute Respiratory Syndrome Coronavirus-2 in Patient With SARS-CoV-2 Admitted in Intensive Care : A Multicenter Retrospective Cohort Study
1 other identifier
observational
1,200
1 country
1
Brief Summary
This study will involve collection of pseudonymized data from hospital-based data reporting at multiple international sites. Collating data from a large volume of patients with COVID-19 admitted in ICU across multiple international sites will enable investigation of whether obesity is a risk factor for complicated from of SARS-CoV-2 in adult patients and whether this association is independent of other cardiometabolic risk factors.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2020
CompletedFirst Submitted
Initial submission to the registry
May 14, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 15, 2020
CompletedFirst Posted
Study publicly available on registry
May 18, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2020
CompletedMarch 26, 2021
May 1, 2020
3 months
May 14, 2020
March 25, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Relationship between body mass index (BMI) and SARS-CoV-2
The primary objective of this study is to investigate the relationship between obesity, as determined by body mass index (BMI), and severe pneumonia, as defined by the need of invasive mechanical ventilation ( IMV), among patient admitted in ICU for SARS-CoV-2, across multiple centers, in multiple countries.
3 months
Secondary Outcomes (3)
Associations between BMI and outcomes is independent of the known cardiometabolic risk factors
3 months
Investigate the modifying effects of age and sex on the associations between BMI and outcome: Invasive mechanical ventilation
3 months
Investigate the modifying effects of age and sex on the associations between BMI and outcome: mortality
3 months
Study Arms (1)
BMI SARS-CoV-2
Patients admitted to Intensive Care Unit with SARS-CoV-2
Interventions
Patients admitted to Intensive Care Unit with SARS-CoV2
Eligibility Criteria
Adult patients admitted to Intensive Care Unit for SARS-CoV-2
You may qualify if:
- Participant is aged 18 years or over
- Has been admitted to ICU with COVID-19 disease.
- COVID-19 disease has been confirmed by PCR for SARS-CoV-2
- Height and weight or BMI on admission has been recorded
- Data has been collected in an ethical manner as part of a national database or clinical auditing process approved by the local institution or collaboration
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centre Hospitalier Régional & Universitaire de Lille (CHRU)
Lille, 59100, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Francois Pattou, MD
Centre Hospitalier Régional & Universitaire de Lille (CHRU)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 14, 2020
First Posted
May 18, 2020
Study Start
February 1, 2020
Primary Completion
May 15, 2020
Study Completion
September 1, 2020
Last Updated
March 26, 2021
Record last verified: 2020-05