Egyptian Initial Experience About 2019 Novel Corona Virus: Study of 48 Patients in Alexandria-Egypt Using Chest CT

NCT04382469 | Completed

• 1 other identifier: IRB (00012098), FWA (00018699)
• Study Type: observational
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Corona virus disease 2019 (COVID-19) is a highly infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Purpose: To give initial experience about COVID-19 in Alexandria-Egypt describing radiological patterns of lung involvement, also surveying prevalence of co-morbid lung diseases and their effect on COVID-19 presentation. Methods: Retrospective study including 48 patients with positive polymerase chain reaction (PCR) test for COVID-19 during the period from February 2020 till May 2020 in Alexandria/Egypt. Full clinical and laboratory data are obtained. High resolution computed tomography (HRCT) findings are described. Serial follow up studies are done. Surveying co-morbid lung diseases done including tuberculosis (TB), interstitial lung diseases (ILDs), chronic obstructive lung disease (COPD), immune and vascular-related diseases. Prevalence rate is the predominant analysis.

Conditions

COVID

Outcome Measures

Primary Outcomes (2)

• Radiological pattern of initial presentation, disease progress, healing and recovery

  HRCT findings

  "through study completion, an average of 1 month"

• Survey of co-morbid lung diseases

  prevalence

  "through study completion, an average of 1 month"

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Primary care centers

You may qualify if:

• Positive COVID-19

You may not qualify if:

• Incomplete medical records, degrade CT images because of patient tachypnea and motions artifacts, also unremarkable CT scans.

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Faculty of Medicine, University of Alexandria

Alexandria, 21526, Egypt

Location

Study Officials

• Ahmed Samir, MD

  Department of Radio-diagnosis.

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of radio-diagnosis

Study Record Dates

• First Submitted: May 5, 2020
• First Posted: May 11, 2020
• Study Start: February 1, 2020
• Primary Completion: April 30, 2020
• Study Completion: May 1, 2020
• Last Updated: May 12, 2020

Record last verified: 2020-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)