Platelet Count, Platelet, Mean Platelet Volume and Platelet Distribution Width in COVID-19

NCT04378829 | Completed

• 1 other identifier: COVID-19
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The study will aim to investigate the relation of platelet count (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) with other acute phase reactant c-reactive protein(CRP) in Coronavirus(COVID-19). As a methodology, patients will be selected in records in one month from the online hospital system. Two groups will be divided before as need for mechanical ventilation or not. The latter comparison will be about three groups as an ambulatory follow-up, hospital follow-up, and intensive care unit follow-up. Parameters will be analyzed according to the groups.

Conditions

Covid-19; Mean Platelet Volume; Platelet Destruction

Outcome Measures

Primary Outcomes (1)

• Change in PDW and MPV parameters

  Expected increase or decrease in parameters according to the course of the disease

  3 weeks totally tests.

Study Arms (3)

ambulatory follow-up

Diagnostic Test: Platelet count, platelet, mean platelet volume and platelet distribution Width in COVID-19

hospital follow-up

Diagnostic Test: Platelet count, platelet, mean platelet volume and platelet distribution Width in COVID-19

intensive care unit follow-up

Diagnostic Test: Platelet count, platelet, mean platelet volume and platelet distribution Width in COVID-19

Interventions

Platelet count, platelet, mean platelet volume and platelet distribution Width in COVID-19 DIAGNOSTIC_TEST

Platelet count, platelet, mean platelet volume and platelet distribution Width in COVID-19

ambulatory follow-up; hospital follow-up; intensive care unit follow-up

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study group will be selected from patients followed up in the 1-month period from the hospital online COVID-19 monitoring system.

You may qualify if:

• Patients diagnosed with COVID-19, both PCR tests and computed tomography, as well as control hemogram and CRP tests at one week intervals will be included.

You may not qualify if:

• Those with suspicion of COVID-19, those who do not perform hemogram and c-reactive protein tests 3 times with one week intervals, those who do not have standard drug treatment will be excluded from the study.

Sponsors & Collaborators

• Konya Meram State Hospital: lead

Study Sites (1)

Yasin Tire

Konya, 42140, Turkey (Türkiye)

Location

MeSH Terms

Conditions

COVID-19

Interventions

Platelet Count; Mean Platelet Volume

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Blood Cell Count; Cell Count; Cytological Techniques; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Hematologic Tests; Platelet Function Tests; Investigative Techniques; Cell Physiological Phenomena; Blood Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena; Cell Size

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: May 3, 2020
• First Posted: May 7, 2020
• Study Start: September 12, 2020
• Primary Completion: October 11, 2020
• Study Completion: October 21, 2020
• Last Updated: September 23, 2021

Record last verified: 2021-09

Locations

TU (1)