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Sponsor study identifier
Secondary identifiers
observational
2,962
1 country
1
Study Start
May 8, 2020
Actual (reported)Primary Completion
May 1, 2021
Actual (reported)Study Completion
November 19, 2021
Actual (reported)Background: Researchers think that people s mental health and behavior will be very affected by the steps taken to slow the spread of COVID-19, such as social distancing. Also, the threat of disease and death, to people and their loved ones, can cause much stress. Researchers want to learn more about these stressors and how they are affecting people. Objective: To study the relationship of affective, cognitive, and behavioral responses to stressors related to COVID-19 with neuroimaging and behavioral data collected before COVID-19. Eligibility: English-speaking adults age 18 and older Design: This online study will include both new participants and those who have taken part in past National Institute of Mental Health studies. All will complete the same surveys and tasks. Participants will give their name and email address. They will get a username and password. The file that links their username to their personal data will be kept secure. Participants will complete a set of surveys about the following:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 19, 2021
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 5, 2020
Actual (reported)May 6, 2020
Actual (reported)May 8, 2020
Actual (reported)May 1, 2021
Actual (reported)November 19, 2021
Actual (reported)Functional connectivity of canonical networks
To examine patterns of neural circuits connectivity as potential predictors of rating scores of affective, cognitive and behavioral (including task performance) responses to COVID-19 among healthy and clinically anxious participants who already participants in SNFA resting-state connectivity studies.
Date of subject participation
Questionnaire data
Date of subject participation
Adults 18 and over
MH COVID-19 Adult, MASQ-SF, STAI, ACS, Hollingshead, DSM XC, PMHC, AUDIT, debriefing questionnaire, and finger-tapping task
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Community sample of adult subjects in the U.S.
National Institute of Mental Health (NIMH)
Bethesda, Maryland, 20892, United States
Ernst M, Cogo-Moreira H, Desai J, Merke DP. Sexual dimorphism in anxiety is programmed in-utero by sex-steroids: Proof of concept using a disease-model and stress responses to COVID pandemic. Psychiatry Res. 2024 Jan;331:115623. doi: 10.1016/j.psychres.2023.115623. Epub 2023 Nov 27.
Maryland Pao, M.D.
National Institute of Mental Health (NIMH)
2,962 participants (actual enrollment reported by the registry).
First Submitted
May 5, 2020
First Posted
May 6, 2020
Study Start
May 8, 2020
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
May 1, 2021
Actual (reported)Study Completion
November 19, 2021
Actual (reported)Last Updated
May 31, 2025
Record last verified: 2025-05
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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