NCT04373161

Brief Summary

The purpose of this study is to investigate the use of home pulse oximetry monitoring in patients with COVID-19 to trend disease progression and identify need for hospitalization.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
209

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 20, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 22, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 22, 2020

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

April 30, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 4, 2020

Completed
Last Updated

May 6, 2020

Status Verified

May 1, 2020

Enrollment Period

1 month

First QC Date

April 30, 2020

Last Update Submit

May 5, 2020

Conditions

Keywords

OximetryOximeterCOVID-19

Outcome Measures

Primary Outcomes (1)

  • Hospitalization in COVID-19 patients with low home SpO2

    The primary outcome is the relative risk of hospitalization in COVID-19 patients with resting home pulse oximeter SpO2 below 92%.

    7 days after enrollment

Secondary Outcomes (7)

  • Trend in resting home pulse oximetry readings

    7 days after enrollment

  • Timing of SpO2 <92%

    7 days after enrollment

  • Home pulse oximeter use effect on subsequent ED visits

    7 days after enrollment

  • Reason for return to the Emergency Department

    7 days after enrollment

  • Hospitalization outcome - morbidity

    Up to 21 days after enrollment

  • +2 more secondary outcomes

Study Arms (1)

Suspected COVID-19 patients being discharged to home

EXPERIMENTAL

Patients will be given a portable, fingertip pulse oximeter to take home. Patients will monitor their resting home oxygen saturation three times per day.

Device: Home Pulse Oximetry Monitoring

Interventions

Patients to check their home oxygen saturation three times daily and return to the ED for sustain oxygen \<92% or for worsening symptoms.

Suspected COVID-19 patients being discharged to home

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with suspected COVID-19 as defined by the World Health Organization
  • Age \> 18

You may not qualify if:

  • Pregnancy
  • Prisoners
  • Lack of decision making capacity or cannot provide consent
  • Patients being admitted to the hospital
  • Patients on home oxygen
  • Patients being discharged to a skilled nursing facility

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Swedish Hospital

Chicago, Illinois, 60625, United States

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Sonia Shah, DO

    Swedish Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physician

Study Record Dates

First Submitted

April 30, 2020

First Posted

May 4, 2020

Study Start

March 20, 2020

Primary Completion

April 22, 2020

Study Completion

April 22, 2020

Last Updated

May 6, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will not share

Locations