Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy
1 other identifier
observational
477
1 country
1
Brief Summary
With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia. The aim of this study was to investigate in patients undergoing total thyroidectomy whether serum calcium and/or PTH levels can predict hypoparathyroidism.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 25, 2020
CompletedStudy Start
First participant enrolled
April 25, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 25, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
April 25, 2020
CompletedFirst Posted
Study publicly available on registry
May 1, 2020
CompletedMay 1, 2020
April 1, 2020
Same day
April 25, 2020
April 30, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
calcium and PTH thresholds
For all 477 patients postoperative calcium and PTH levels and treatment with calcium and vitamin D will be analyzed. Objective is to identify the calcium and PTH thresholds at which the patient after total thyroidectomy can be discharged without risk of hypocalcemia.
one years
Study Arms (1)
477 patients
the biological tests of 477 patients undergoing total thyroidectomy were analyzed
Interventions
Eligibility Criteria
Analysis of calcium and PTH levels in postoperative day 1
You may qualify if:
- Total thyroidectomy
You may not qualify if:
- concomitant parathyroidectomy for primary hyperparathyroidism
- lobectomy only
- completion thyroidectomy
- central and lateral neck dissection
- patients with calcium and/or vitamin D supplementation prior surgery
- patients with known and significant osteoporosis and renal failure
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Conception Hospital
Marseille, 13005, France
Related Publications (1)
Paladino NC, Guerin C, Graziani J, Morange I, Loundou A, Taieb D, Sebag F. Predicting risk factors of postoperative hypocalcemia after total thyroidectomy: is safe discharge without supplementation possible? A large cohort study. Langenbecks Arch Surg. 2021 Nov;406(7):2425-2431. doi: 10.1007/s00423-021-02237-2. Epub 2021 Aug 10.
PMID: 34374848DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
April 25, 2020
First Posted
May 1, 2020
Study Start
April 25, 2020
Primary Completion
April 25, 2020
Study Completion
April 25, 2020
Last Updated
May 1, 2020
Record last verified: 2020-04
Data Sharing
- IPD Sharing
- Will not share
the data are confidential