Key Insights

Highlights

Success Rate

91% trial completion (above average)

Published Results

18 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

6.2%

5 terminated out of 81 trials

Success Rate

90.6%

+4.0% vs benchmark

Late-Stage Pipeline

22%

18 trials in Phase 3/4

Results Transparency

38%

18 of 48 completed with results

Key Signals

18 with results91% success

Data Visualizations

Phase Distribution

50Total
Not Applicable (9)
Early P 1 (3)
P 1 (8)
P 2 (12)
P 3 (15)
P 4 (3)

Trial Status

Completed48
Recruiting13
Unknown6
Terminated5
Not Yet Recruiting3
Suspended3

Trial Success Rate

90.6%

Benchmark: 86.6%

Based on 48 completed trials

Clinical Trials (81)

Showing 20 of 20 trials
NCT07081997Phase 3RecruitingPrimary

A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism

NCT07540286Phase 2SuspendedPrimary

A Cohort Study on the Safety and Efficacy of XH-02 in Treating Hypoparathyroidism

NCT07530705Phase 1SuspendedPrimary

Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism

NCT07699471Phase 3RecruitingPrimary

A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism

NCT07197450Early Phase 1SuspendedPrimary

Efficacy and Safety of XH02 for the Treatment of Hypoparathyroidism

NCT07805356Phase 3RecruitingPrimary

Efficacy, Safety, and Tolerability of Encaleret in Participants With Chronic Hypoparathyroidism

NCT05114980Not ApplicableWithdrawnPrimary

Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism

NCT06547151Phase 2Active Not RecruitingPrimary

Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adults

NCT07264634RecruitingPrimary

A Study to Assess the Amount of Palopegteriparatide in Breast Milk of Lactating Females Requiring YORVIPATH® (Palopegteriparatide)

NCT07706764Phase 3RecruitingPrimary

A Study to Test the Effects and Safety of Palopegteriparatide in Adolescents With Long-term Hypoparathyroidism

NCT01922440CompletedPrimary

A Registry for Participants With Chronic Hypoparathyroidism

NCT04701203Phase 3CompletedPrimary

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism

NCT02924532CompletedPrimary

Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thyroidectomy

NCT04009291Phase 2CompletedPrimary

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism

NCT07617584Not ApplicableNot Yet Recruiting

NIRAF-Guided Parathyroid Identification During Thyroidectomy

NCT07083557Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

NCT06465108Phase 2CompletedPrimary

Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism

NCT00743782Phase 2CompletedPrimary

Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidism

NCT07345494RecruitingPrimary

A Global Pregnancy Registry to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to YORVIPATH® (Palopegteriparatide) During Pregnancy and Breastfeeding

NCT06961071Phase 1RecruitingPrimary

Parathyroid Allotransplant for Treatment of Hypoparathyroidism

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