The CEDiD Study (COVID-19 Early Diagnosis in Doctors and Healthcare Workers)
CEDiD
1 other identifier
observational
60
1 country
1
Brief Summary
This is a prospective observational cohort study of healthcare workers working in high-risk COVID-19 clinical areas, monitoring heart rate, sleep and temperature, correlating with daily self-reported symptoms, oxygen saturations and PCR Swabs. It will provide information about how many healthcare workers develop COVID-19, what their clinical observations and symptoms are.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Aug 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 23, 2020
CompletedFirst Posted
Study publicly available on registry
April 27, 2020
CompletedStudy Start
First participant enrolled
August 20, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2021
CompletedMarch 19, 2021
April 1, 2020
9 months
April 23, 2020
March 18, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
COVID-19 Infection
Number of Healthcare Workers who have a new PCR positive diagnosis of COVID-19
30 days
Secondary Outcomes (2)
Symptoms
30 days
Clinical Observations
30 days
Interventions
A wearable medical device (Empatica E4) which is a smart wristband that detects skin temperature, heart rate and sleep. It is CE and FDA approved.
COVID-19 PCR Swab will be self-taken by doctors every day. Fischer nasopharyngeal PCR Swabs
Participants will measure their oxygen saturations every day, and report them on the survey. Pulmolink A310 pulse oximeters
Eligibility Criteria
Healthy healthcare workers who work in high-risk COVID-19 areas, and have not themselves had a PCR/Antibody positive diagnosis of COVID-19
You may qualify if:
- Healthy healthcare professionals of any age
You may not qualify if:
- Previous PCR/Antibody positive test for COVID-19
- Not working in high-risk COVID-19 area (ICU, A\&E, COVID positive wards)
- Involved in COVID-19 Vaccine Trial
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- King's College Londonlead
- Guy's and St Thomas' NHS Foundation Trustcollaborator
Study Sites (1)
Guy's and St Thomas' NHS Foundation Trust
London, United Kingdom
Related Publications (1)
Zargaran A, Sousi S, Colville G, Radcliffe G, Malek R, Douiri A, El-Boghdadly K, Nebbia G, Martinez Nunez RT, Greenough A. COVID-19 Early Detection in Doctors and Healthcare Workers (CEDiD) study: a cohort study on the feasibility of wearable devices. BMJ Open. 2025 Apr 5;15(4):e089598. doi: 10.1136/bmjopen-2024-089598.
PMID: 40187781DERIVED
Biospecimen
COVID-19 PCR Swabs
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Alexander Zargaran, MBBS
King's College London / Guy's and St Thomas' NHS Foundation Trust
- STUDY CHAIR
Anne Greenough
King's College London
- STUDY DIRECTOR
Dina Radenkovic, MBBS
King's College London / Guy's and St Thomas' NHS Foundation Trust
- STUDY DIRECTOR
Rocio Martinez-Nunez, PhD
King's College London
- PRINCIPAL INVESTIGATOR
Kariem El-Boghdadly
Guy's and St Thomas' NHS Foundation Trust
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 23, 2020
First Posted
April 27, 2020
Study Start
August 20, 2020
Primary Completion
May 30, 2021
Study Completion
June 30, 2021
Last Updated
March 19, 2021
Record last verified: 2020-04