CORonavirus (COVID-19) Diagnostic Lung UltraSound Study
COR-DLUS
1 other identifier
observational
45
1 country
1
Brief Summary
This observational study is designed to assess whether focused lung ultrasound examination can improve the diagnosis of COVID-19 lung disease and/or make an alternative diagnosis at a patient's initial hospital presentation. For patients with confirmed COVID-19 the study will also assess whether surveillance lung ultrasound examination can predict clinical outcome over the course of their hospital admission.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 16, 2020
CompletedFirst Posted
Study publicly available on registry
April 17, 2020
CompletedStudy Start
First participant enrolled
May 11, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 15, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
February 15, 2021
CompletedOctober 15, 2021
October 1, 2021
9 months
April 16, 2020
October 14, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Diagnosis of COVID-19 on lung ultrasound
Primary and blinded scorer diagnosis of COVID-19 on lung ultrasound
On day of admission to hospital
Difference in diagnosis of COVID-19 on lung ultrasound vs. chest x-ray
Primary and blinded scorer diagnosis of COVID-19 on lung ultrasound vs. radiologist-reported chest x-ray findings
On day of admission to hospital
Secondary Outcomes (3)
Diagnosis of alternative condition to COVID-19 on lung ultrasound vs. chest x-ray
On day of admission to hospital
Ability of surveillance lung ultrasound to predict clinical trajectory / outcome in patients with COVID-19
During hospital admission
Consistency of lung ultrasound interpretation in patients presenting with suspected COVID-19
On day of admission to hospital
Interventions
Focused lung ultrasound examination
Eligibility Criteria
Adult patients (greater than or equal to 18 years in age) presenting with suspected COVID-19
You may qualify if:
- Age greater than or equal to 18 years
- Suspected or confirmed diagnosis of COVID-19
- Able to provide informed consent to study participation
You may not qualify if:
- Age less than 18 years
- Inability to provide informed consent at the time of study enrolment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Derriford Hospital
Plymouth, Devon, PL6 8DH, United Kingdom
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
John P Corcoran, BMBCh MRCP
University Hospitals Plymouth NHS Trust
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 16, 2020
First Posted
April 17, 2020
Study Start
May 11, 2020
Primary Completion
February 15, 2021
Study Completion
February 15, 2021
Last Updated
October 15, 2021
Record last verified: 2021-10
Data Sharing
- IPD Sharing
- Will not share