NCT04357912

Brief Summary

The purpose of this study is to evaluate standard of care exercise education alone or in combination with a wearable physical activity tracker in people with epilepsy (PWE) to determine the most effective way to increase physical activity and measure impact on depression, anxiety, quality of life, sleep, and seizure frequency.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 20, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 22, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

June 16, 2020

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 2, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 2, 2022

Completed
Last Updated

December 5, 2023

Status Verified

December 1, 2023

Enrollment Period

2.2 years

First QC Date

April 20, 2020

Last Update Submit

December 1, 2023

Conditions

Keywords

epilepsyexerciseactivity tracker

Outcome Measures

Primary Outcomes (3)

  • Number of steps taken by participant

    3 months after enrollment

  • Total distance traveled by participant

    3 months after enrollment

  • Total time participant is active

    measured in minutes

    3 months after enrollment

Secondary Outcomes (8)

  • Depression as measured by the Patient Health Questionnaire depression scale (PHQ-9)

    Baseline

  • Depression as measured by the Patient Health Questionnaire depression scale (PHQ-9)

    end of study (3 months after enrollment)

  • Anxiety as measured by the General Anxiety Disorder 7-item scale (GAD-7)

    Baseline

  • Anxiety as measured by the General Anxiety Disorder 7-item scale (GAD-7)

    end of study (3 months after enrollment)

  • Sleep as measures by the Epworth Sleepiness Scale (ESS)

    Baseline

  • +3 more secondary outcomes

Study Arms (2)

Experimental group

EXPERIMENTAL
Behavioral: Activity Tracker Group

Control Group

ACTIVE COMPARATOR
Behavioral: Standard of Care Group

Interventions

In addition to the standard of care exercise education, participants in the activity tracker group will be provided a Fitbit physical activity tracker at no cost to the participants. They will be asked to download the Fitbit application (app) to their personal smartphone device to allow them to see their own data collected by the Fitbit. They will also be asked to download the Stridekick app for the purpose of sharing their activity tracker data electronically with the study team and having the opportunity to participate in fitness challenges through the app. App accounts will be created by the participants with usernames that do not contain the participant's identifiable personal information. Optional fitness challenges will be created once per month by the study investigators, and participants will also receive a weekly message of encouragement from the study team.

Experimental group

Participants will receive standard of care exercise education.

Control Group

Eligibility Criteria

Age18 Years - 64 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • patient of the Texas Comprehensive Epilepsy Program at UTHealth-McGovern Medical School
  • diagnosis of epilepsy
  • be able to provide consent in English
  • complete surveys independently
  • be able to sync Fitbit data

You may not qualify if:

  • currently using a wearable physical activity tracker prior to enrollment
  • pregnant or planning to become pregnant during the study duration
  • planning to undergo epilepsy surgery during the study duration

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States

Location

MeSH Terms

Conditions

EpilepsyMotor Activity

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesBehavior

Study Officials

  • Katherine Harris, MD

    The University of Texas Health Science Center, Houston

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Fellow

Study Record Dates

First Submitted

April 20, 2020

First Posted

April 22, 2020

Study Start

June 16, 2020

Primary Completion

September 2, 2022

Study Completion

September 2, 2022

Last Updated

December 5, 2023

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will not share

Locations