NCT04352283

Brief Summary

Obesity is associated with difficulties in epidural space catheterization. The investigators want to prove that a pre-procedural ultrasound exam of lumbar spine increase the first-pass success rate of the epidural space identification among obese parturients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 6, 2019

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 8, 2019

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2020

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 29, 2020

Completed
22 days until next milestone

First Posted

Study publicly available on registry

April 20, 2020

Completed
Last Updated

May 5, 2020

Status Verified

March 1, 2019

Enrollment Period

2 days

First QC Date

March 29, 2020

Last Update Submit

May 4, 2020

Conditions

Keywords

ultrasoundobesityepidural analgesiavaginal delivery

Outcome Measures

Primary Outcomes (1)

  • Success of the epidural space identification at the first needle pass

    Succes rate of the epidural space identification at the first needle pass (first skin puncture and without needle redirection) for each group

    Baseline up to 1 hour

Secondary Outcomes (11)

  • Success of the epidural space identification at the first skin puncture

    Baseline up to 1 hour

  • Number of skin punctures

    Baseline up to 1 hour

  • Number of needle redirections

    Baseline up to 1 hour

  • Number of intervertebral space punctured

    Baseline up to 1 hour

  • Duration of the epidural procedure

    Baseline up to 1 hour

  • +6 more secondary outcomes

Study Arms (2)

palpation

NO INTERVENTION

Usual method to determinate needle puncture site

Ultrasound

EXPERIMENTAL

Ultrasound preprocedural exam used to determinate needle puncture site

Device: Preprocedural ultrasound exam of lumbar spine

Interventions

Preprocedural ultrasound exam of lumbar spine used to determinate needle puncture site

Ultrasound

Eligibility Criteria

Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Full-term parturients (≥ 37 weeks of amenorrhea)
  • With pre-pregnancy BMI ≥ 30 kg/m2
  • Admit for a vaginal delivery
  • Receiving labour epidural analgesia

You may not qualify if:

  • Usual contraindications for neuraxial anesthesia (thrombocytopenia, coagulopathy, uncorrected hypovolemia, infected puncture site, intracranial hypertension)
  • Emergency maternal and foetal cases
  • Twin pregnancy
  • Marked spinal deformity ou previous spinal surgery
  • Refusal to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital of Cote de Nacre

Caen, 14000, France

Location

Related Publications (1)

  • Balki M. Locating the epidural space in obstetric patients-ultrasound a useful tool: continuing professional development. Can J Anaesth. 2010 Dec;57(12):1111-26. doi: 10.1007/s12630-010-9397-y. Epub 2010 Nov 11. English, French.

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Lise-Amelie ZERAJIC, MD

    Anesthesiologist Intensivist Physician

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: randomized controlled open trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 29, 2020

First Posted

April 20, 2020

Study Start

April 6, 2019

Primary Completion

April 8, 2019

Study Completion

February 28, 2020

Last Updated

May 5, 2020

Record last verified: 2019-03

Data Sharing

IPD Sharing
Will not share

Locations