NCT04350788

Brief Summary

The purpose of this research study is to examine the feasibility of the enhanced survivorship care plans (ESCPs, regular SCPs with the a web-based couple-focused symptom self-management project (PERC) or National Cancer Institute prostate cancer web links) and to conduct an initial benefit assessment of enhanced survivorship care plans among prostate cancer patients transitioning from active treatment to post-treatment self-management, and their partners. Participation of this study lasts for about for 16 weeks. Depending on participants' need for information, it takes 10-30 minutes of their time each week to review the information about prostate cancer. Eligible and consented patients with newly treated localized prostate cancer and your partner (couples) are randomly assigned to the regular survivorship care plan (SCPs) with the NCI website or the enhanced survivorship care plans (SCP plus the web-based prostate cancer education program, PERC) groups. They complete baseline (T1, prior to randomization) and 4-month post-T1 follow-up measures (T2).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
124

participants targeted

Target at P50-P75 for not_applicable prostate-cancer

Timeline
Completed

Started Aug 2017

Shorter than P25 for not_applicable prostate-cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 3, 2017

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2018

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 15, 2019

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

March 28, 2020

Completed
20 days until next milestone

First Posted

Study publicly available on registry

April 17, 2020

Completed
5 months until next milestone

Results Posted

Study results publicly available

September 23, 2020

Completed
Last Updated

September 23, 2020

Status Verified

September 1, 2020

Enrollment Period

1.3 years

First QC Date

March 28, 2020

Results QC Date

June 11, 2020

Last Update Submit

September 3, 2020

Conditions

Keywords

survivorship care planquality of lifesupportive care

Outcome Measures

Primary Outcomes (5)

  • Percentage of Potentially Eligible Participants Actually Enrolled Into the Study

    Will evaluate the percentage of patients and partners successfully consented and completing the baseline survey among all people approached for the study

    after participants completed baseline survey

  • Percentage of Participants Enrolled Who Remained in the Study and Completed the Post-Intervention Follow-Up Survey

    Will evaluate the percentage of participants successfully following protocol, defined as completing the Follow-Up survey at the end of the study period among those who have been enrolled into the study (who completed the baseline).

    during 4-month study period

  • Percentage of Participants That Used the Web-Based Intervention Sessions That Are Consistent With Patient-Reported Symptoms

    The usage of Web-Based Intervention Sessions is determined by the percentage of participants who logged into the study website among those who have been randomly assigned to the intervention group. Patient-Reported Symptoms are determined by patient's responses on their appraisal of prostate cancer symptoms and general symptoms. 1=patient reported the symptom and the symptom webpage reviewed; 0=patient reported the symptom and no related webpage reviewed OR patient did not report the symptom but the webpage reviewed

    during 4-month study period

  • Participant Satisfaction Scores

    Program satisfaction determined by the 11-item Participant Satisfaction Scale measured the level of program satisfaction. The first to tenth items ranged from 1=not satisfied to 5=extremely satisfied. The eleventh item ranged from 1=extremely not to 4=definitely yes. Higher total score indicates greater program satisfaction

    at the 4 month followup

  • Perceived Ease of Use Score

    The 16-item Program Usability measures participants' assessment of their agreement with the ease of use of the program in terms of its general features, content, and navigation. The ranges of the total scores are (3,15), (4,20), (9,45) for general features, content, and navigation, respectively. The score of individual item ranges from1=strongly disagree to 5=strongly agree. Higher score indicates greater perceived ease of use.

    at the 4 month followup

Secondary Outcomes (10)

  • Change in FACT-G Scores

    Baseline upon enrollment, Month 4

  • Change in Appraisal of Prostate Cancer-Specific Symptoms

    Baseline upon enrollment, Month 4

  • Change in Appraisal of General Symptoms

    Baseline upon enrollment, Month 4

  • Healthcare Utilization Extracted From Electronic Medical Record

    during the first 10 months after participants completed baseline survey

  • Change in Self-Efficacy Scores From Baseline to 4-Months Post Baseline

    Baseline upon enrollment, Month 4

  • +5 more secondary outcomes

Study Arms (2)

Survivorship Care Plan (SCP)

PLACEBO COMPARATOR

The SCP group (control) participants were directed to the National Cancer Institute PC website (NCI) (http://www.cancer.gov/types/prostate),

Other: Survivorship Care Plan

Enhanced SCP (ESCP)

EXPERIMENTAL

ESCP consists of the standard SCP that is enhanced by a couple-focused, tailored mHealth PC education program, the Patient Education Resources for Couples, to improve symptom management at home.

Other: Enhanced Survivorship Care Plan

Interventions

Participants visit the NCI prostate cancer website in addition to their standardized post-treatment survivorship care

Survivorship Care Plan (SCP)

In addition to their standardized post-treatment survivorship care, participants visit the prostate cancer education resources for couples (PERC) website that was based on scientific evidence and input from stakeholders including PC patients, partners, and cancer care providers. Participants learn about skills and knowledge about how to enhance their positive appraisals of symptoms and self-efficacy in symptom management through information and skills training, fostering healthy behaviors, and facilitating social support

Enhanced SCP (ESCP)

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Eligibility included men who:
  • were diagnosed with localized PC;
  • were within 16 weeks of completing their initial curative intent treatment \[26\] at genitourinary and radiation oncology clinics at two comprehensive cancer centers in the U.S southeast;
  • were not treated for another cancer in last year; and
  • had a partner \> 18 years of age not receiving cancer treatment.

You may not qualify if:

  • Either member of couple unable to speak English
  • Unwilling/unable to provide Informed Consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27559, United States

Location

Related Publications (1)

  • Song L, Guo P, Tan X, Chen RC, Nielsen ME, Birken SA, Koontz BF, Northouse LL, Mayer DK. Enhancing survivorship care planning for patients with localized prostate cancer using a couple-focused web-based, mHealth program: the results of a pilot feasibility study. J Cancer Surviv. 2021 Feb;15(1):99-108. doi: 10.1007/s11764-020-00914-7. Epub 2020 Jul 17.

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Results Point of Contact

Title
Biostatistician
Organization
UNC-CH School of Nursing

Study Officials

  • Lixin Song, RN, PhD

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 28, 2020

First Posted

April 17, 2020

Study Start

August 3, 2017

Primary Completion

November 30, 2018

Study Completion

April 15, 2019

Last Updated

September 23, 2020

Results First Posted

September 23, 2020

Record last verified: 2020-09

Data Sharing

IPD Sharing
Will share

Deidentified individual data that supports the results will be shared beginning 9 to 36 months following publication provided the investigator who proposes to use the data has approval from an Institutional Review Board (IRB), Independent Ethics Committee (IEC), or Research Ethics Board (REB), as applicable, and executes a data use/sharing agreement with UNC.

Time Frame
9 to 36 months following publication
Access Criteria
Investigator who proposes to use the data has approval from an IRB, IEC, or REB, as applicable, and an executed data use/sharing agreement with UNC.

Locations