NCT04348253

Brief Summary

Comparison of two surgical techniques commonly used for reconstruction of the scapholunate (SL) ligament. A randomized multicenter study.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
85mo left

Started Aug 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress53%
Aug 2018Apr 2033

Study Start

First participant enrolled

August 1, 2018

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

March 30, 2020

Completed
17 days until next milestone

First Posted

Study publicly available on registry

April 16, 2020

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2023

Completed
10 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2033

Expected
Last Updated

April 16, 2020

Status Verified

March 1, 2020

Enrollment Period

4.7 years

First QC Date

March 30, 2020

Last Update Submit

April 15, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • The Disabilities of the Arm, Shoulder and Hand Score (QuickDash)

    points

    At all follow-ups (0-10 years)

Secondary Outcomes (4)

  • Grip-strength

    At all follow-ups (0-10 years)

  • SL angle

    At all follow-ups (0-10 years)

  • The Patient-Rated Wrist Evaluation (PRWE) score

    At all follow-ups (0-10 years)

  • Wrist motion

    At all follow-ups (0-10 years)

Study Arms (2)

Berger

ACTIVE COMPARATOR

Bergers capsulodesis

Procedure: Berger

3LT

ACTIVE COMPARATOR

Three ligament tenodesis

Procedure: 3LT

Interventions

BergerPROCEDURE

Treatment 1

Berger
3LTPROCEDURE

Treatment 2

3LT

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age 18-60 years (both included).
  • Symptomatic SL instability (VAS score ³3, QDASH score ³ 20).
  • \> 6 weeks since symptomatic hand trauma (chronic SL lesions).
  • SL gapping on radiographic stress views or SL gapping (³2mm) on static PA views.
  • Complete SL ligament lesion confirmed by wrist arthroscopy

You may not qualify if:

  • Geissler grade 1-3 SLL injury (evaluated by arthroscopy).
  • Concomitant complete luno-triquetral (LT) ligament injury (evaluated by arthroscopy).
  • Lesion of TFCC leading to DRUJ instability (evaluated by arthroscopy).
  • Radiocarpal or midcarpal arthritis evaluated by arthroscopy.
  • Previous fracture in carpus or intraarticular radius fracture with step off (³2 mm), disposing to posttraumatic arthritis.
  • Adverse effects after extra articular radial fractures (dorsal angulation ³10 grader).
  • Peroperatively non-reducible scaphoid flexion/SL gap.
  • Terminal illness or severe medical illness: ASA score higher than or equal to 3.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Aarhus University Hospital

Aarhus, 8200, Denmark

RECRUITING

Hospital Unit Vest

Holstebro, 7500, Denmark

RECRUITING

Study Officials

  • Janni K Thillemann, Dr

    Hospitalsenheden Vest

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Janni K Thillemann, Dr

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
Scares are identical. Patient and examiner are blinded
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: randomized trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 30, 2020

First Posted

April 16, 2020

Study Start

August 1, 2018

Primary Completion

April 30, 2023

Study Completion (Estimated)

April 30, 2033

Last Updated

April 16, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share

Locations