NCT04347759

Brief Summary

This project aims to adapt a computer-interface telephonic interactive voice response system that monitors symptoms and provides real-time, self-management coaching messages based on heart failure patient-reported outcomes.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable heart-failure

Timeline
Completed

Started Feb 2023

Typical duration for not_applicable heart-failure

Geographic Reach
1 country

4 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 1, 2020

Completed
14 days until next milestone

First Posted

Study publicly available on registry

April 15, 2020

Completed
2.8 years until next milestone

Study Start

First participant enrolled

February 12, 2023

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2026

Completed
Last Updated

March 13, 2026

Status Verified

February 1, 2026

Enrollment Period

3.2 years

First QC Date

April 1, 2020

Last Update Submit

March 11, 2026

Conditions

Keywords

Symptom ManagementTechnology

Outcome Measures

Primary Outcomes (1)

  • Self-Care of Heart Failure Index (SCHFI) Score

    The Self-Care of Heart Failure Index, version 7.2, is a 29-item instrument with separate scales assessing self-care maintenance, symptom perception, and self-care management. Responses to items are given on a 5-point scale. Scores for each of the three scales are summed and standardized with scores ranging from 0 to 100. Higher scores indicate better self-care, with scores of 70 or higher indicating adequate levels of heart failure self-care.

    Baseline (at the time of hospital discharge, pre-intervention), Day 30 (post-intervention)

Secondary Outcomes (4)

  • Number of eligible patients recruited

    Baseline (at the time of hospital discharge, pre-intervention)

  • Number of participants using the intervention

    Up to Day 30 (post-intervention)

  • Days on Study

    Up to Day 30 (post-intervention)

  • Satisfaction with Phone Calls

    Day 30 (post-intervention)

Other Outcomes (1)

  • Number of Participants Re-hospitalized

    Up to 30 days after hospital discharge

Study Arms (2)

Symptom Care at Home with Coaching Messages

EXPERIMENTAL

Participants randomized to automated daily monitoring and real-time self-management coaching.

Behavioral: Coaching MessagesBehavioral: Automated Daily Monitoring

Usual Care

ACTIVE COMPARATOR

Participants randomized to automated daily monitoring only.

Behavioral: Automated Daily Monitoring

Interventions

Participants receive real-time self-management coaching messages based on the severity of their symptoms. When participants call, the IVR system will ask them about each of the selected symptoms, and the patient will report symptom presence and severity numerically with the touch-tone keypad.

Symptom Care at Home with Coaching Messages

Participants report daily symptoms and symptom severity. There are three categories of severity based on a numeric scale of 1 to 3 for mild symptoms, 4 to 7 for moderate symptoms, and 8 to 10 for severe symptoms.

Symptom Care at Home with Coaching MessagesUsual Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Medical diagnosis of heart failure
  • New York Heart Association (NYHA) Classification of the Stages of Heart Failure Class I - IV
  • Ability to read, understand, and speak in English
  • Will be discharged home
  • Has daily access to any type of telephone

You may not qualify if:

  • A score of 0 or 1-2 with an abnormally drawn clock on the Mini-Cog
  • Discharged home on hospice care
  • End-stage renal failure
  • Wait list for heart transplant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States

RECRUITING

Emory Clinic

Atlanta, Georgia, 30322, United States

RECRUITING

Emory University Hospital

Atlanta, Georgia, 30322, United States

RECRUITING

University of Utah Health

Salt Lake City, Utah, 84112, United States

COMPLETED

MeSH Terms

Conditions

Heart FailureSigns and Symptoms

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesPathological Conditions, Signs and Symptoms

Study Officials

  • Youjeong Kang, PhD

    Emory University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Youjeong Kang, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

April 1, 2020

First Posted

April 15, 2020

Study Start

February 12, 2023

Primary Completion

April 30, 2026

Study Completion

April 30, 2026

Last Updated

March 13, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

De-identified data will be made available for sharing with other researchers.

Shared Documents
STUDY PROTOCOL
Time Frame
Data will be made available for sharing following publication of findings from this study.
Access Criteria
Researchers who want to share de-identified data from this study must complete a data use agreement. Those wanting to share data from this study should contact Dr. Kang at youjeong.kang@emory.edu.

Locations