Trials Sponsors Conditions Drugs Pricing

Conditions

Hyperthyroidism Melasma

Keywords

Melasmamodified melasma area and severity indexThyroid stimulating hormoneFree thyroxine

Outcome Measures

Primary Outcomes (1)

mMASI (modified melasma area and severity index)
mMASI Score (modified melasma area and severity index); value 0-24; smaller score means better outcome
3 months after taking the hyperthyroid drugs

Other Outcomes (1)

Proportion of melasma in hyperthyroid patients
3 months

Study Arms (1)

Single Intervention

OTHER

Before-and-After type of research

Drug: Thiamazol

Interventions

ThiamazolDrug

All new hyperthyroid with melasma patients were recruited and their mMASI were calculated All subjects were given thiamazole by Internist based on their clinical hyperthyroidism After 3 months of taking hyperthyroid drugs (thiamazole), mMASI were recalculated and compared

Single Intervention

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 60 Years

Sexfemale(Gender-based eligibility)

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Female with age range of 18 to 60 years old
Newly diagnosed with hyperthyroid on a laboratory basis

Sponsors & Collaborators

Dr.dr.Irma Bernadette, SpKK (K)
Otherlead

Study Sites (1)

dr. Cipto Mangunkusumo Hospital

Jakarta, Jakarta Pusat, 10430, Indonesia

MeSH Terms

Conditions

MelanosisHyperthyroidism

Interventions

Methimazole

Condition Hierarchy (Ancestors)

HyperpigmentationPigmentation DisordersSkin DiseasesSkin and Connective Tissue DiseasesThyroid DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Sulfhydryl CompoundsSulfur CompoundsOrganic ChemicalsImidazoles

Study Officials

Irma B Sitohang, MD, PhD
Fakultas Kedokteran Universitas Indonesia
PRINCIPAL INVESTIGATOR

Enrollment

23 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: phase 1
Allocation: NA
Masking: NONE
Purpose: OTHER
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Irma Bernadette S. Sitohang, MD, PhD - Head of Division of Cosmetic Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Study Record Dates

First Submitted

April 10, 2020

First Posted

April 15, 2020

Study Start

August 1, 2019

Actual (reported)

Comparative Study of mMASI Before and After Hyperthyroid Therapy in Hyperthyroid Subjects With Melasma

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Other Outcomes (1)

Study Arms (1)

Single Intervention

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Other Outcomes (1)

Study Arms (1)

Single Intervention

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations