NCT04319432

Brief Summary

Aim of Study: To determine the optimal duration of voice rest following phonosurgery for patients who undergo phonosurgery due to benign vocal cord lesions IE: vocal fold nodules, cysts, polyps, granulomas, leukoplakia, and subepithelial edema.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 12, 2018

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

March 19, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 24, 2020

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

March 24, 2020

Status Verified

March 1, 2020

Enrollment Period

4.2 years

First QC Date

March 19, 2020

Last Update Submit

March 23, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • better voice quality by GRABS scale

    GRABS scale- Grade, Roughness, Breathiness, Asthenia, Strain (GRBAS) each ranked from 0 to 3

    6 months post op

Study Arms (2)

3 days voice rest

EXPERIMENTAL
Behavioral: Voice rest

7 days voice rest

EXPERIMENTAL
Behavioral: Voice rest

Interventions

Voice restBEHAVIORAL

The first days will take place in hospitalization to assess patient complience to voice rest. Patients will be instructed to continue voice rest at home up to 7 days accourding to group allocation in the study. The confirmation of voice rest will relay on patient report (telephonic approval), after the voice rest period will end.

3 days voice rest7 days voice rest

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who undergo phonosurgery for benign vocal fold lesions.
  • Adults (18-90years).
  • Patients who can provide and give informed consent.

You may not qualify if:

  • Patients without a complete medical record
  • Patients who are unable or unwilling to give informed consent
  • Patients younger than 18 years of age or older then 90 years
  • Patients who are pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

TASMC

Tel Aviv, Israel

RECRUITING

Study Officials

  • Yael Oestreicher kedem, MD

    TASMC

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Yael Oestreicher Kedem, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Prospective Study. In this study, patients will be placed into one of two different groups of voice rest duration. The voice rest durations will last either 3 or 7 days. Voice recording results of the different groups will be examined and analyzed. At the conclusion of this study, we hope to provide some clarity as to the optimal duration of voice rest following phonosurgery.
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 19, 2020

First Posted

March 24, 2020

Study Start

October 12, 2018

Primary Completion

December 31, 2022

Study Completion

December 31, 2022

Last Updated

March 24, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share

Anonymization of study patients Patient information (I.e. name, ID number, etc.) will be collected and kept confidential throughout the study so that the patients cannot be re-traced or identified. The information will be gathered by the main investigator kept in an encrypted file with a password required for access on the main researcher's computer. Information will not be sent or distributed outside the hospital to anyone.

Locations