NCT04315675

Brief Summary

HIV is no longer a death sentence, and with adherence to Rapid High Activity Antiretroviral (HAART) protocol women with HIV can achieve a normal life expectancy. In New Jersey there are 11,724 (32.9%) women living with HIV with Essex county in the lead, and they come they come from lowest social strata and educational level and are often single mothers. The purpose of this study is test three study interventions: a cognitive health promotion intervention, a guided imagery intervention and combination of both interventions. The Significance of the study is to improve the functional health and protocol adherence, to better enable women with HIV to achieve a normal life expectancy. The Methodology is an intervention study that uses a classic four group pretest post-test experimental design with random assignment, and the subjects for the study will be 80 women living with HIV. The interventions will be delivered within a three-week time frame followed by post testing at the end of the third week in Newark,New Jersey. The results of this study will be used as preliminary data to support a grant proposal to be submitted to the National Institutes of Health. The Results of this study are important as they will support improved health function and adherence to treatment protocols for marginalized poor women with HIV to achieve outcomes on par with men.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 28, 2020

Completed
20 days until next milestone

First Posted

Study publicly available on registry

March 19, 2020

Completed
13 days until next milestone

Study Start

First participant enrolled

April 1, 2020

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2020

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

March 19, 2020

Status Verified

March 1, 2020

Enrollment Period

9 months

First QC Date

February 28, 2020

Last Update Submit

March 18, 2020

Conditions

Keywords

Promoting functional health

Outcome Measures

Primary Outcomes (8)

  • CD4 Counts

    Cells in human body measure response immune system to infection

    Measured at the baseline

  • CD4 Counts

    Cells in human body measure response immune system to infection

    Measured 21 days after the baseline

  • Viral Load

    Sero blood assessment of amount of HIV virus.

    At the baseline

  • Viral Load

    Sero blood assessment of amount of HIV virus

    Twenty-one days following the baseline

  • SF-36v2 Health Survey

    Functional Health from the participants perspective

    At the baseline

  • SF-36v2 Health Survey

    Functional Health from the participants perspective

    Twenty-one days after the baseline

  • Power as Knowing Participation in Change (PKPCT)

    Subjects Power Profile to Create Change

    At the Baseline.

  • Power as Knowing Participation in Change (PKPCT)

    Subjects Power Profile to Create Change

    Twenty-one days after the baseline.

Study Arms (4)

Guided Imagery Intervention

EXPERIMENTAL

Participants randomly assigned to this group will be provided with a MP3 Player which will have three guided imagery programs The Guided Imagery Programs include: 1.) Relaxation and Wellness; 2.) Immune System Imagery; and 3.) Healing Trauma.

Behavioral: Guided Imagery Intervention

Cognitive Power Intervention

EXPERIMENTAL

The participant who is randomly assigned to this group completes The Power as Knowing Participation in Change Version II (PKPCT) to determine 1.) Freedom to Act Intentionally, 2.) Involvement in Creating Change, 3.) Freedom to Act Intentionally and 4.) My Involvement in Creating Change.

Behavioral: Cognitive Power Intervention

Cognitive Power Intervention and Guided Imagery

EXPERIMENTAL

The participant is randomly assigned to this group completes both the Guided Imagery Intervention and the Cognitive Power Intervention.

Behavioral: Combined Guided Imagery and Cognitive Power Intervention

Control Group

NO INTERVENTION

The participant is randomized to the control group and completes all study measures twenty-one days after the baseline data are competed. .

Interventions

The participant listens to a selected Guided Imagery for 21 consecutive days.

Guided Imagery Intervention

The participant develops a plan to achieve healthy outcomes and reviews plan for 21 consecutive days.

Cognitive Power Intervention

The participant completes 21 days of selected Guided Imagery in combination with the development of a plan to achieve healthy outcomes and reviews the plan for 21 days.

Cognitive Power Intervention and Guided Imagery

Eligibility Criteria

Age18 Years - 80 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsWomen diagnosed with HIV.
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women participants diagnosed with HIV
  • Must speak and write in English

You may not qualify if:

  • Women participants with debilitating complications
  • Women participants with Cognitive Impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seton Hall University, College of Nursing

Nutley, New Jersey, 07110, United States

Location

Related Publications (4)

  • Barrett EA. Power as knowing participation in change: what's new and what's next. Nurs Sci Q. 2010 Jan;23(1):47-54. doi: 10.1177/0894318409353797.

    PMID: 20026728BACKGROUND
  • Caroselli C, Barrett EA. A review of the power as knowing participation in change literature. Nurs Sci Q. 1998 Spring;11(1):9-16. doi: 10.1177/089431849801100105.

    PMID: 9555424BACKGROUND
  • Hansell PS, Hughes CB, Caliandro G, Russo P, Budin WC, Hartman B, Hernandez OC. The effect of a social support boosting intervention on stress, coping, and social support in caregivers of children with HIV/AIDS. Nurs Res. 1998 Mar-Apr;47(2):79-86. doi: 10.1097/00006199-199803000-00006.

    PMID: 9536191BACKGROUND
  • Hansell PS, Hughes CB, Caliandro G, Russo P, Budin WC, Hartman B, Hernandez OC. Boosting social support in caregivers of children with HIV/AIDS. AIDS Patient Care STDS. 1999 May;13(5):297-302. doi: 10.1089/apc.1999.13.297.

    PMID: 10356809BACKGROUND

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

HIV InfectionsBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesSlow Virus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Study Officials

  • Phyllis S Hansell, EdD

    Seton Hall University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Michael La Fountaine, EdD

CONTACT

Franklin Williams

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: This is a quantitative intervention study that tests and compares outcomes of three interventions and a control group. The subjects are randomly assigned to one of four study groups.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 28, 2020

First Posted

March 19, 2020

Study Start

April 1, 2020

Primary Completion

December 30, 2020

Study Completion

December 31, 2020

Last Updated

March 19, 2020

Record last verified: 2020-03

Locations