Power Training on Muscle Quality and Functional Capacity in Women Aged 65-75.

NCT04315662 | Unknown

• 1 other identifier: CI5302
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

Muscle power training has proven to be an effective intervention to prevent sarcopenia and frailty in old people. In the last decade, new concepts related to the functionality of old people have been generated, such as muscle quality and functional capacity. The power training consists of rapid movements of short duration that imply a more specialized neuromuscular response and that improve the functional response reflected in activities of daily life that demand a certain manifestation of muscular power (stand up of a chair, climbing stairs, rebalance, accelerate suddenly, among others). Therefore, it is important to investigate the dose-response relationships in power training in older people and establish how possible improvements in muscle quality can be reflected in functional capacity. The aim of this study is to compare the effects of power training at two different loads on muscle quality and functional capacity in women aged 65-75

Conditions

Muscle Weakness; Muscle Loss

Keywords

Muscle quality; Functional capacity; Power training

Outcome Measures

Primary Outcomes (1)

• Change on muscle quality: obtained by measuring mean leg extension power divided by muscle mass of thighs

  The muscle quality will be obtained by measuring mean leg extension power divided by muscle mass of thighs (measured by dual-energy x-ray absorptiometry)

  Baseline and after 8 weeks

Secondary Outcomes (3)

• Change on chair stand test

  Baseline and after 8 weeks

• Change on time up go test with cognitive task

  Baseline and after 8 weeks

• Change on gait speed test

  Baseline and after 8 weeks

Study Arms (2)

Muscle power training with velocity loss (VL) of 10%

EXPERIMENTAL

Subjects followed a muscle power training for 8 weeks (2 sessions per week on alternate days) using the leg extension exercise, with similar relative intensity (50% 1RM). Between weeks one and four two series will be performed per session. Then the number of series will increase to three per session. The inter-set recovery period will be always of 2-min. Velocity loss will be of 10% (VL10) in each set.

Other: Muscle power training with velocity loss (VL) of 10%

Muscle power training with velocity loss (VL) of 30%

ACTIVE COMPARATOR

Subjects followed a muscle power training for 8 weeks (2 sessions per week on alternate days) using the leg extension exercise, with similar relative intensity (50% 1RM). Between weeks one and four two series will be performed per session. Then the number of series will increase to three per session. The inter-set recovery period will be always of 2-min. Velocity loss will be of 30% (VL30) in each set.

Other: Muscle power training with velocity loss (VL) of 30%

Interventions

Muscle power training with velocity loss (VL) of 10% OTHER

Subjects followed a muscle power training for 8 weeks (2 sessions per week on alternate days) using the leg extension exercise, with similar relative intensity (50% 1RM). Between weeks one and four two series will be performed per session. Then the number of series will increase to three per session. The inter-set recovery period will be always of 2-min. Velocity loss will be of 10% (VL10) in each set.

Muscle power training with velocity loss (VL) of 10%

Muscle power training with velocity loss (VL) of 30% OTHER

Subjects followed a muscle power training for 8 weeks (2 sessions per week on alternate days) using the leg extension exercise, with similar relative intensity (50% 1RM). Between weeks one and four two series will be performed per session. Then the number of series will increase to three per session. The inter-set recovery period will be always of 2-min. Velocity loss will be of 30% (VL30) in each set.

Muscle power training with velocity loss (VL) of 30%

Eligibility Criteria

• Age: 65 Years - 75 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Women 65 to 75 years.
• Healthy volunteers.
• Have not perform muscle power training in the last six months.

You may not qualify if:

• History of asthma.
• History of uncontrolled diabetes.
• History of uncontrolled hypertension.
• History of cardiovascular disease.
• History of coronary heart disease.
• Smoker.
• Arrhythmias.
• Personal history of surgical procedures in the last three months.
• Uncontrolled non-communicable diseases.
• Psychological, sensitive, cognitive, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.
• Under medical treatment with anticoagulants, bronchodilators, and/or steroids.

Sponsors & Collaborators

• Universidad del Valle, Colombia: lead
• Universidad de Antioquia: collaborator

Study Sites (1)

Universidad del Valle

Cali, Valle del Cauca Department, Colombia

Location

MeSH Terms

Conditions

Muscle Weakness; Muscular Atrophy

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Atrophy; Pathological Conditions, Anatomical

Study Officials

• Santiago A Arboleda, Ph.D.

  Universidad del Valle, Cali, Colombia.

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Santiago A Arboleda, Ph.D.

CONTACT

+573164459690; santiago.arboleda@correounivalle.edu.co

Fredy A Patiño, Ph.D.

CONTACT

+573167849453; fredy.patino@udea.edu.co

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 9, 2020
• First Posted: March 19, 2020
• Study Start: May 1, 2020
• Primary Completion: November 30, 2020
• Study Completion: February 11, 2021
• Last Updated: March 19, 2020

Record last verified: 2020-03

Data Sharing

• IPD Sharing: Will not share

Locations

CO (1)