Key Insights

Highlights

Success Rate

85% trial completion

Published Results

27 trials with published results (31%)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

8.0%

7 terminated out of 87 trials

Success Rate

84.8%

-1.7% vs benchmark

Late-Stage Pipeline

33%

29 trials in Phase 3/4

Results Transparency

69%

27 of 39 completed with results

Key Signals

27 with results85% success

Data Visualizations

Phase Distribution

75Total
Not Applicable (2)
Early P 1 (1)
P 1 (15)
P 2 (28)
P 3 (25)
P 4 (4)

Trial Status

Completed39
Recruiting15
Unknown10
Active Not Recruiting10
Terminated7
Withdrawn3

Trial Success Rate

84.8%

Benchmark: 86.5%

Based on 39 completed trials

Clinical Trials (87)

Showing 20 of 20 trials
NCT05677451Phase 3RecruitingPrimary

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

NCT07256392Phase 3RecruitingPrimary

Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT07540910Phase 1Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy Adults

NCT07358364RecruitingPrimary

Remibrutinib in Real-world Clinical Practice

NCT07316114RecruitingPrimary

A Study to Describe the Real-world Effectiveness, Safety and Patterns of Use of Dupilumab in Patients With Chronic Spontaneous Urticaria

NCT07219615Phase 2RecruitingPrimary

A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

NCT06873516Phase 2Active Not RecruitingPrimary

Phase 2b Study of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria (CSU)

NCT06445023Phase 3Active Not RecruitingPrimary

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT06455202Phase 3Active Not RecruitingPrimary

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)

NCT03661866Active Not Recruiting

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

NCT05936567Phase 2Completed

Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticaria

NCT05513001Phase 3Active Not RecruitingPrimary

An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib

NCT06042478Phase 3Active Not RecruitingPrimary

Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.

NCT07408219RecruitingPrimary

A Real-world Study of Remibrutinib in Chronic Spontaneous Urticaria Patients

NCT06931405Phase 2Recruiting

Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

NCT07358780RecruitingPrimary

Remibrutinib in Real-world Clinical Practice - a US Sub-study

NCT07402213Phase 3Not Yet RecruitingPrimary

Trial of JYB1904 Injection in Adult Patients With Chronic Spontaneous Urticaria.

NCT06053801CompletedPrimary

A Real-world Study to Assess Safety and Effectiveness of Xolair® in Pediatric Chronic Spontaneous Urticaria in China

NCT07005713Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple-Ascending Doses of BGB-16673 in Adults With Chronic Spontaneous Urticaria

NCT06162728Phase 1Active Not RecruitingPrimary

Dose Escalation Trial Of Safety, Pharmacokinetic/Pharmacodynamic And Preliminary Clinical Activity of Briquilimab In Adult Patients With Chronic Spontaneous Urticaria (CSU)

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