Key Insights

Highlights

Success Rate

84% trial completion

Published Results

28 trials with published results (31%)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

8.8%

8 terminated out of 91 trials

Success Rate

84.3%

-2.2% vs benchmark

Late-Stage Pipeline

32%

29 trials in Phase 3/4

Results Transparency

65%

28 of 43 completed with results

Key Signals

28 with results84% success

Data Visualizations

Phase Distribution

78Total
Not Applicable (2)
Early P 1 (2)
P 1 (16)
P 2 (29)
P 3 (25)
P 4 (4)

Trial Status

Completed43
Recruiting12
Active Not Recruiting11
Unknown10
Terminated8
Withdrawn3

Trial Success Rate

84.3%

Benchmark: 86.6%

Based on 43 completed trials

Clinical Trials (91)

Showing 20 of 20 trials
NCT07686484Early Phase 1RecruitingPrimary

A Trial of HRS-3095 in Healthy Volunteers

NCT07642557RecruitingPrimary

Remibrutinib in Real-world Clinical Practice - a Germany Sub-study (REASSERT)

NCT05107115Phase 2CompletedPrimary

Rilzabrutinib for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine

NCT06162728Phase 1CompletedPrimary

Dose Escalation Trial Of Safety, Pharmacokinetic/Pharmacodynamic And Preliminary Clinical Activity of Briquilimab In Adult Patients With Chronic Spontaneous Urticaria (CSU)

NCT07402213Phase 3RecruitingPrimary

Trial of JYB1904 Injection in Adult Patients With Chronic Spontaneous Urticaria.

NCT07316114TerminatedPrimary

A Study to Describe the Real-world Effectiveness, Safety and Patterns of Use of Dupilumab in Patients With Chronic Spontaneous Urticaria

NCT07256392Phase 3Enrolling By InvitationPrimary

Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT06931405Phase 2Active Not Recruiting

Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

NCT07717905Phase 1RecruitingPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics and Clinical Activity of BBT001 Following Intravenous Administration in Participants With Chronic Spontaneous Urticaria (CSU)

NCT05677451Phase 3Active Not RecruitingPrimary

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

NCT06873516Phase 2CompletedPrimary

Phase 2b Study of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria (CSU)

NCT07005713Phase 1CompletedPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple-Ascending Doses of BGB-16673 in Adults With Chronic Spontaneous Urticaria

NCT07219615Phase 2RecruitingPrimary

A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

NCT07230418Phase 1CompletedPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Doses of HRS-3095 Oral Administration in Healthy Subjects, as Well as the Effect of HRS-3095 on CYP3A4 Metabolic Enzymes

NCT06396026Phase 3Active Not RecruitingPrimary

A Study of Efficacy and Safety of TLL-018 in CSU Participants

NCT06042478Phase 3Active Not RecruitingPrimary

Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.

NCT07613866Phase 2Not Yet RecruitingPrimary

A Clinical Trial of HRS-3095 in Patients With Chronic Spontaneous Urticaria

NCT07408219RecruitingPrimary

A Real-world Study of Remibrutinib in Chronic Spontaneous Urticaria Patients

NCT06365879Phase 3Active Not RecruitingPrimary

To Compare Efficacy and Safety of CMAB007 and Xolair® in Patients With Chronic Spontaneous Urticaria

NCT07540910Phase 1Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy Adults

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