10-week Yoga Practice Effect on Cognitive and Motor Function in Older Adults
BDNF
10-week Yoga Practice Effect in Older Adults
1 other identifier
interventional
33
1 country
1
Brief Summary
Thirty-three healthy elderly people, who were classified into two age groups, participated in this study. All participants had not practiced yoga before and were asked not to perform any sports activities while the research was ongoing. In the experimental group, participants (n = 18) had to participate in 10 weeks of yoga classes. In the control group, participants (n = 15) did not perform any exercises or other changes in their daily living life. Experimental measurements: Brunel, PSS-14 and HAD questionnaires
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Oct 2018
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 30, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
September 30, 2019
CompletedFirst Submitted
Initial submission to the registry
March 17, 2020
CompletedFirst Posted
Study publicly available on registry
March 19, 2020
CompletedMarch 20, 2020
March 1, 2020
12 months
March 17, 2020
March 18, 2020
Conditions
Outcome Measures
Primary Outcomes (8)
Brunel mood scale (BRUMS)
The Lithuanian translated version of the Brunel Mood Scale (BRUMS) was used in the present study. It was based on the originally developed to serve as a brief measure of mood before and after yoga intervention. The BRUMS (1) scale has 24 items arranged into six subscales: anger, confusion, depression, fatigue, tension and vigor. Each subscale has a numerical rating scale (0 = not at all, 1 = a bit, 2 = moderate, 3 = enough; 4 = extremely) from which research participant select the one best represents at that time. The results within subscale is summed and a score range from 0 to 16
10 weeks
Hospital anxiety and depression scale (HADS)
To determine the level of anxiety and depression of subjects was used HADS scale. The scale consists of totally 14 questions with the answers valued from 0 to 3. Half of questions addressed to estimate anxiety and rest - depression. The total scoring and conclusion for the both categories of questions: 0-7 = Normal; 8-10 = Borderline abnormal (borderline case); 11-21 = Abnormal (case)
10 weeks
Perceived stress scale -14
The purpose of this scale is to assess the degree of stress in subjects' lives. It consists of questions about the frequency of feeling and thoughts during the past time period. Potential answers: 0-never; 1-almost never; 2-sometimes; 3-fairly often and 4-very often. The scores are obtained by reversing the scores on the four positive items: for example, 0=4, 1=3, 2=2, etc. and then summing across all items. Scores for the 14-item form range from 0 to 56, with higher scores indicating greater perceived stress
10 weeks
Human Free BDNF
Venous blood samples from median antecubital vein were collected in 5 ml vacuum tubes with a gel separator and was separated by centrifugation (15 min at 1200g) to make blood serum. Samples were aliquoted and stored at -800C until analysis. The serum concentration of Human Free BDNF was measured using an enzyme-linked immunoassay kit (R\&D Systems, Minneapolis, USA)
10 weeks
Measurement of cognitive functions
Automated Neuropsychological Assessment Metrics Version 4 (ANAM-4; Vista Life, USA) was used to measure neurocognitive skills: mental flexibility, verbal working memory, inhibition control, visuospatial processing.
10 weeks
Psychomotor function evaluation
Participants were assessed by Dynamic Parameter Analyzer (DPA-1). Its measure motor functions: accuracy, reaction speed-accuracy.
10 weeks
Heart rate variability
R-R intervals were recorded using a Polar H7 sensor with a chest strap (Kempele, Finland).
10 weeks
Balance procedure
Postural sway activity was measured by a posturography method with a single piezoelectric force plate (Kistler, Slimline System 9286, Switzerland).
10 weeks
Study Arms (2)
10-week Yoga
EXPERIMENTALEighteen healthy elderly people, who were classified into two age groups, participated in this study. All participants had not practiced yoga before and were asked not to perform any sports activities while the research was ongoing. In the experimental group, participants (n = 18) had to participate in 10 weeks of yoga classes. In the control group, participants (n = 15) did not perform any exercises or other changes in their daily living life. All experimental group subjects participated in Himalayan yoga classes, which lasted 10 weeks: 2 times per week, 90 min per session. Yoga classes were conducted by 16-year-old qualified yoga instructor from Yoga Academy, Kaunas.
Control
NO INTERVENTIONIn the control group, participants (n = 15) did not perform any exercises or other changes in their daily living life.
Interventions
Eligibility Criteria
You may qualify if:
- age, from 60 years old
- a statement by a local family physician about general good physical health
- never tired to practice yoga before
You may not qualify if:
- cardiovascular diseases
- musculoskeletal system diseases (osteoporosis, osteochondrosis, hernias)
- neurodegenerative diseases
- oncological diseases
- glaucoma
- injuries and surgeries in last 3 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Lithuanian Sports Unviersity
Kaunas, 44221, Lithuania
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 17, 2020
First Posted
March 19, 2020
Study Start
October 1, 2018
Primary Completion
September 30, 2019
Study Completion
September 30, 2019
Last Updated
March 20, 2020
Record last verified: 2020-03
Data Sharing
- IPD Sharing
- Will not share