The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance

NCT04292106 | Completed

• 1 other identifier: 092619
• Study Type: interventional
• Target: 11
• Locations: 1 country
• Sites: 1

Brief Summary

Red Spinach is a natural food which is a rich source of nitrates, which are beneficial in hemodynamics, cardiovascular function, and have natural hypotensive and antianginal effects. Red spinach extract has been shown to be beneficial in exercise performance, albeit mostly in aerobic exercise. In a previous study in our lab, we found that dietary nitrate consumption resulted in significantly greater isometric force production in teenage males. However, currently there is little know regarding the effects of dietary nitrate supplementation on isometric strength, resistance exercise and cognitive performance.

Conditions

Sports

Outcome Measures

Primary Outcomes (4)

• Bench Press Repetitions to Fatiuge

  Number of repetitions completed in each set during the acute exercise bout will be recorded and analyzed

  Through study completion, during both treatments (~4 weeks)

• Bench Press Power

  Power during bench press repetitions will be measured via a linear transducer.

  Through study completion, during both treatments (~4 weeks)

• Isometric Mid-thigh pull (IMTP) Peak Force

  Peak Force will be measured via dual force plates during a full-body isometric strength test.

  Through study completion, during both treatments (~4 weeks)

• Isometric Mid-thigh pull (IMTP) Rate of Force Development

  Rate of Force development will be measured via dual force plates during a full-body isometric strength test.

  Through study completion, during both treatments (~4 weeks)

Secondary Outcomes (2)

• Estimated Muscle Blood Flow via Near-infrared Spectroscopy (NIRS)

  Through study completion, during both treatments (~4 weeks)

• Cognitive Performance via Stroop Test

  Through study completion, during both treatments (~4 weeks)

Study Arms (2)

Placebo

PLACEBO COMPARATOR

Dietary Supplement: Placebo

Red Spinach Extract (RSE)

EXPERIMENTAL

Dietary Supplement: Red Spinach Extract (RSE)

Interventions

Red Spinach Extract (RSE) DIETARY_SUPPLEMENT

Oral capsules containing 2g of Red Spinach Extract will be consumed daily for 7 days

Red Spinach Extract (RSE)

Placebo DIETARY_SUPPLEMENT

Oral placebo capsules will be taken consisting of maltodrextrin daily for 7 days

Placebo

Eligibility Criteria

• Age: 18 Years - 34 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• years old Participants must have at least 1 year of resistance training experience.
• Free of any physical limitations, medications, and supplements that may affect performance, as determined by a health and activity questionnaire.
• Are free of musculoskeletal injuries
• Are not taking medications that may interfere with study measurements

You may not qualify if:

• Participants that cannot take either the RSE or placebo supplement will be excluded, as this will be a double-blind study.
• Furthermore, participants that cannot participate in pre- and post-research testing, and/or those that cannot commit to regular training sessions will be excluded.
• Inability to perform physical exercise (determined by health and activity questionnaire)
• Taking any other nutritional supplement or performance enhancing drug.
• Any chronic illness that causes continuous medical care

Sponsors & Collaborators

• Lipscomb University: lead

Study Sites (1)

Jeremy Townsend

Nashville, Tennessee, 37215, United States

Location

Study Officials

• Jeremy Townsend, PhD

  Lipscomb University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: January 17, 2020
• First Posted: March 2, 2020
• Study Start: September 26, 2019
• Primary Completion: March 30, 2020
• Study Completion: March 30, 2020
• Last Updated: January 14, 2022

Record last verified: 2022-01

Locations

US (1)