Physical Activity, Meal Composition, and RMR Among Children Adolescent and Adults
1 other identifier
interventional
21
1 country
2
Brief Summary
Resting metabolic rate (RMR) is the amount of energy the body uses at rest, and accounts for 60%-70% of daily energy expenditure. Although measured at rest, RMR is strongly influenced by physical activity because the increased metabolic rate during exercise is partially carried over even when exercise stops. Therefore, persons who are physically active maintain higher RMR and less body fat than do sedentary controls. It is well known that high energy intake stimulates whereas caloric restriction reduces RMR. Food thermogenesis corresponds to approximately 10% of daily energy expenditure. Diet-induced thermogenesis is greater on a high protein and carbohydrate diet than on a fat diet. Other factors the affect RMR are age (RMR tends to decline progressively over the life span) and body composition (lean body mass is regarded as the main determinant of RMR). However, the research regarding the effect of a specific combination of macronutrients and exercise on RMR is scarce. Therefore, the aim of the current study is to assess the combined effect of a meal composition and physical activity on RMR in normal weight and overweight children, adolescents and adults.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable obesity
Started Mar 2019
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2019
CompletedFirst Submitted
Initial submission to the registry
March 17, 2019
CompletedFirst Posted
Study publicly available on registry
February 26, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 29, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
September 29, 2020
CompletedSeptember 30, 2020
September 1, 2020
1.6 years
March 17, 2019
September 29, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change in RMR from baseline
Resting Metabolic Rate
Through study completion, an average of 6 weeks (during 4 visits)
Study Arms (1)
Normal and overweight participants
EXPERIMENTALHealthy males and female, age 6 to 30. BMI range for participants age 6 to 18 is between 5th percentile to 85th percentile, overweight BMI between the 85 and 95th percentile, and obese, above the 95th percentile. BMI range for participants age 18 to 30 is between 18.5 to 24.9 for normal weight, 25-30 for overweight and above 30 for obese.
Interventions
Following exercise participants will consume a drink (with different composition in each visit) and than RMR will be evaluated.
Eligibility Criteria
You may qualify if:
- Ages 6-30 years.
- Normal weight and over weight participants
You may not qualify if:
- Elite athletes
- Participants with physical limitations concerning strenuous physical activity.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
'Meir children's sport and health center'
Kfar Saba, 44281, Israel
Meir Medical Center
Kfar Saba, 44281, Israel
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Dan Nemet, MD
Meir Medical Center
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Prof. Dan Nemet
Study Record Dates
First Submitted
March 17, 2019
First Posted
February 26, 2020
Study Start
March 1, 2019
Primary Completion
September 29, 2020
Study Completion
September 29, 2020
Last Updated
September 30, 2020
Record last verified: 2020-09
Data Sharing
- IPD Sharing
- Will not share