Postpartum Depression
The Effect of the Anesthesia Modality Used in Women Giving Birth Under Caesarian Section on Postpartum Depression and/or Postoperative Melatonin Levels
1 other identifier
observational
300
1 country
1
Brief Summary
Our aim was to diagnose and initiate early treatment for postpartum depression by detecting the changes of melatonin levels in c-sections with different antesthesia modalities.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 18, 2020
CompletedFirst Posted
Study publicly available on registry
February 20, 2020
CompletedStudy Start
First participant enrolled
March 21, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 21, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
July 21, 2020
CompletedFebruary 20, 2020
February 1, 2020
2 months
February 18, 2020
February 18, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
edinburgh depression scale
below 12 is associated with depression
5 months
Study Arms (3)
general anesthesia
c-section with general anesthesia
spinal anesthesia
c-section with spinal anesthesia
epidural anesthesia
c-section with epidural anesthesia
Interventions
melatonin levels in c-sections with different anesthesia modalities.
Eligibility Criteria
pregnant women that will give birth by c-section (using general or regional anesthesia) aged between 18-45 years will be included to our study
You may qualify if:
- pregnant women c-section (using general or regional anesthesia) aged between 18-45 years
You may not qualify if:
- age under 18 or above 45, history of smoking, a diagnosis with mental retardation, psychiatric patients, use of antipsychotics or antidepressants, patients with sleeping disorders, hormone replacement theraphy patients.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Erzincan Byu
Erzincan, Turkey (Türkiye)
Related Publications (3)
Andersen LP, Werner MU, Rosenberg J, Gogenur I. A systematic review of peri-operative melatonin. Anaesthesia. 2014 Oct;69(10):1163-71. doi: 10.1111/anae.12717. Epub 2014 May 19.
PMID: 24835540RESULTMaitra S, Baidya DK, Khanna P. Melatonin in perioperative medicine: Current perspective. Saudi J Anaesth. 2013 Jul;7(3):315-21. doi: 10.4103/1658-354X.115316.
PMID: 24015137RESULTDianatkhah M, Ghaeli P, Hajhossein Talasaz A, Karimi A, Salehiomran A, Bina P, Jalali A, Ghaffary S, Shahmansouri N, Vejdani S. Evaluating the Potential Effect of Melatonin on the post-Cardiac Surgery Sleep Disorder. J Tehran Heart Cent. 2015 Jul 3;10(3):122-8.
PMID: 26697084RESULT
Biospecimen
blood samples
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Remziye Ayşenur NALBANT
ERZİNCAN
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Week
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
February 18, 2020
First Posted
February 20, 2020
Study Start
March 21, 2020
Primary Completion
May 21, 2020
Study Completion
July 21, 2020
Last Updated
February 20, 2020
Record last verified: 2020-02
Data Sharing
- IPD Sharing
- Will not share