Serotonin, Leptin and Adiponectin Level in Patients With Postpartum Depression: Controlled Study
1 other identifier
observational
400
1 country
1
Brief Summary
After vaginal delivery, all of the participants will evaluate by using Edinburg depression scale and venous blood sample will obtain. Postpartum depression will consider the result of scale 13 and above according to Turkhish translate. Then leptin, adiponectin and serotonin level will compare between depressed and nondepressed women.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2016
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2016
CompletedFirst Submitted
Initial submission to the registry
February 10, 2016
CompletedFirst Posted
Study publicly available on registry
February 15, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2017
CompletedMarch 15, 2022
March 1, 2022
1.2 years
February 10, 2016
March 13, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Blood level (ng/ml) ELİSA
1 month
Study Arms (2)
Women with postpartum depression
Women without postpartum depression
Interventions
Eligibility Criteria
According to Edinburg depression scale womenn who taken 13 point and above.
You may qualify if:
- All women who gave birth
You may not qualify if:
- women with previously diagnosed depression and any psychiatric disorders
- women with previously take antidepressan and antipshycothic
- women giving birth to children with anomalies
- women with undertake surgery for peripartum hemorrhage
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Istanbul, 34668, Turkey (Türkiye)
Related Publications (3)
Hu Y, Dong X, Chen J. Adiponectin and depression: A meta-analysis. Biomed Rep. 2015 Jan;3(1):38-42. doi: 10.3892/br.2014.372. Epub 2014 Oct 16.
PMID: 25469244RESULTSkalkidou A, Sylven SM, Papadopoulos FC, Olovsson M, Larsson A, Sundstrom-Poromaa I. Risk of postpartum depression in association with serum leptin and interleukin-6 levels at delivery: a nested case-control study within the UPPSAT cohort. Psychoneuroendocrinology. 2009 Oct;34(9):1329-37. doi: 10.1016/j.psyneuen.2009.04.003. Epub 2009 May 7.
PMID: 19427131RESULTMansur RB, Rizzo LB, Santos CM, Asevedo E, Cunha GR, Noto MN, Pedrini M, Zeni M, Cordeiro Q, McIntyre RS, Brietzke E. Adipokines, metabolic dysfunction and illness course in bipolar disorder. J Psychiatr Res. 2016 Mar;74:63-9. doi: 10.1016/j.jpsychires.2015.12.003. Epub 2015 Dec 12.
PMID: 26748249RESULT
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
February 10, 2016
First Posted
February 15, 2016
Study Start
February 1, 2016
Primary Completion
April 1, 2017
Study Completion
May 1, 2017
Last Updated
March 15, 2022
Record last verified: 2022-03