NCT04270240

Brief Summary

Patent ductus arteriosus (PDA) is an important morbidity of that the diagnosis and treatment is controversy in premature infants. A number of scoring systems have been developed, including the findings of echocardiography on the diagnosis and treatment of PDA. This study aimed to develop a new clinical scoring system that will enable the rapid, standard and noninvasive evaluation of hemodynamically significant PDA earlier, without relying on echocardiographic findings in premature babies with extremely low birth weight, and to determine the role of this scoring system in early diagnosis and treatment.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2019

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 15, 2019

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

February 12, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 17, 2020

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 15, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 15, 2021

Completed
Last Updated

May 6, 2020

Status Verified

May 1, 2020

Enrollment Period

1.9 years

First QC Date

February 12, 2020

Last Update Submit

May 5, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Participants with Patent Ductus Arteriosus

    number of participants who diagnosed for hemodynamically significant PDA and had an elevated score of the newly developed system by us.

    7 days

Eligibility Criteria

AgeUp to 15 Days
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Infants who born before 28 gestational week and under 1000g of weight will be included.

You may qualify if:

  • informed consent obtained from parents
  • extremely preterm infants
  • infants born before 28 gestational week

You may not qualify if:

  • lack of informed consent
  • chromosomal abnormality
  • cardiovascular abnormality

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seda Yilmaz Semerci

Istanbul, 34303, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Ductus Arteriosus, PatentPremature Birth

Condition Hierarchy (Ancestors)

Heart Defects, CongenitalCardiovascular AbnormalitiesCardiovascular DiseasesHeart DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesObstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Central Study Contacts

Merih Y Cetinkaya

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Neonatologist

Study Record Dates

First Submitted

February 12, 2020

First Posted

February 17, 2020

Study Start

January 15, 2019

Primary Completion

December 15, 2020

Study Completion

February 15, 2021

Last Updated

May 6, 2020

Record last verified: 2020-05

Locations