Key Insights

Highlights

Success Rate

81% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

11.8%

10 terminated out of 85 trials

Success Rate

80.8%

-5.7% vs benchmark

Late-Stage Pipeline

16%

14 trials in Phase 3/4

Results Transparency

21%

9 of 42 completed with results

Key Signals

9 with results81% success

Data Visualizations

Phase Distribution

51Total
Not Applicable (21)
Early P 1 (1)
P 1 (3)
P 2 (12)
P 3 (7)
P 4 (7)

Trial Status

Completed42
Unknown18
Terminated10
Withdrawn4
Active Not Recruiting4
Recruiting4

Trial Success Rate

80.8%

Benchmark: 86.5%

Based on 42 completed trials

Clinical Trials (85)

Showing 20 of 20 trials
NCT03701074Phase 2TerminatedPrimary

Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus

NCT06646250Recruiting

NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot

NCT07533721CompletedPrimary

Ibuprofen vs Expectant Management for hsPDA in Preterm Infants: Retrospective Cohort

NCT06298344Early Phase 1Completed

The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease

NCT03782610Active Not RecruitingPrimary

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes

NCT06658496RecruitingPrimary

PDA for Kidneys Study

NCT05264753RecruitingPrimary

Post Marketing Clinical Follow Up Study to Evaluate Efficacy and Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects

NCT04371081Active Not RecruitingPrimary

Amplatzer Piccolo Occluder Japan Post-marketing Database Surveillance

NCT03456336Phase 3Active Not Recruiting

Management of the PDA Trial

NCT07143201Phase 2RecruitingPrimary

Precision Dosing of Oral Ibuprofen for PDA, A Pilot RCT

NCT05639309CompletedPrimary

Liver Regional Oxygen Saturation in Preterm Patent Ductus Arteriosus

NCT04667455Not ApplicableEnrolling By Invitation

Improving Care for Children With Congenital Heart Disease.

NCT03055858Not ApplicableCompletedPrimary

AMPLATZER Duct Occluder II Additional Sizes

NCT03648437Phase 1TerminatedPrimary

Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus

NCT04347720CompletedPrimary

Canadian National PDA Treatment Study

NCT01479218Not ApplicableCompletedPrimary

Safety and Effectiveness Study With a New PDA Occluder for Closure of Patent Ductus Arteriosus

NCT06256211Phase 1Not Yet RecruitingPrimary

Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates

NCT03982342Not ApplicableTerminatedPrimary

Preliminary Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low-weight Infants

NCT02739087Not ApplicableActive Not Recruiting

Radiation-Free Heart Catheterization Using MRI

NCT06152796Phase 2UnknownPrimary

Comparision Between Paracetamol and Ibuprofen in Closure of Patent Ductus Arteriosus

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