Using the Roots of a Non Restorable Wisdom Tooth as a Block for Augmentation of Localized Defects

NCT04266652 | Unknown Phase 4 DMC

• 1 other identifier: 121734
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

assess and compare the efficacy and safety of autogenous tooth roots for lateral alveolar ridge augmentation with staged implant placement in comparison to autogenous bone block.

Conditions

Augmentation

Keywords

tooth block; Dental implants

Outcome Measures

Primary Outcomes (1)

• Clinical and radiographic assessment of alveolar bone width following autogenous tooth roots augmentation.

  6 months postoperatively

Secondary Outcomes (1)

• Histological analysis of remodeled autogenous bone roots 4 months following horizontal ridge augmentation. Histological analysis of remodeled autogenous bone roots 4 months following horizontal ridge augmentation.

  6 months postoperatively

Study Arms (2)

Autogenous bone block

EXPERIMENTAL

the monocortical block grafts were harvested from the retromolar region (i.e. linea oblique) by using of rotating (i.e. carbide burs)

Procedure: autogenous bone block

Tooth block

EXPERIMENTAL

In the first group, a second mucoperiosteal flap was elevated to surgically remove the respective wisdom tooth. After its removal and during the same surgery, the crown was decapitated at the cemento -enamel junction using a rotating carbide bur under gentle sterile saline cooling and the exposed pulp was preserved. The separated tooth root was adapted to match the size and shape of the defect area. To improve ankylosis between the graft and the defect site, the layer of cementum at the respective downward aspects of the root was carefully removed using a diamond bur until the underlying dentin was entirely exposed

Procedure: tooth block

Interventions

tooth block PROCEDURE

tooth root blocks were used to increase the bone width

Tooth block

autogenous bone block PROCEDURE

autogenous bone block were used to increase the bone width

Autogenous bone block

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Candidate for lateral ridge augmentation
• Insufficient bone ridge width at the recipient site for implant placement
• Sufficient bone height at the recipient site for implant placement
• Healthy oral mucosa, at least 3 mm keratinized tissue.
• Presence of wisdom teeth free from periapical infection.
• Missing maxillary or mandibular tooth with moderate horizontal defect (4-8) according to cologne classification

You may not qualify if:

• \) Patients are systemically free according to Modified Cornell Medical Index 2) smokers patients. 3) Pregnant or lactating women.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Abbassia, 11566, Egypt

RECRUITING

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer Periodontology, Faculty of Dentistry

Study Record Dates

• First Submitted: January 29, 2020
• First Posted: February 12, 2020
• Study Start: January 6, 2018
• Primary Completion: August 15, 2020
• Study Completion: September 30, 2020
• Last Updated: July 22, 2020

Record last verified: 2020-07

Locations

EG (1)