Epidemiologic and Clinical Characteristics of Optic Neuritis in China
1 other identifier
observational
1,000
1 country
1
Brief Summary
This will be a hospital-based retrospective multi-center study on epidemiologic and clinical characteristics of optic neuritis among Chinese. The investigation will cover about 29 provinces or municipalities all around China.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 4, 2020
CompletedFirst Posted
Study publicly available on registry
February 6, 2020
CompletedStudy Start
First participant enrolled
May 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 3, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2021
CompletedJanuary 20, 2021
January 1, 2021
7 months
February 4, 2020
January 17, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Visual Acuity
Last visual acuity records in the hospital
At least 1 year from the attack to the final visit
Annual Relapse Rate
Calculated annual relapse rate of different subgroups in the cohort
At least 1 year from the attack to the final visit
Secondary Outcomes (4)
Epidemiologic characteristics of optic neuritis
At least 1 year from the attack to the final visit
Clinical characteristics of optic neuritis
At least 1 year from the attack to the final visit
Optical Coherence Tomography
At least 1 year from the attack to the final visit
Orbit or Brain MRI at the attack
At least 1 year from the attack to the final visit
Study Arms (1)
optic neuritis
Aquaporin 4 antibody seropositive optic neuritis patients, Myelin oligodendrocyte glycoprotein antibody seropositive optic neuritis patients, and double antibodies seronegative optic neuritis patients
Interventions
Eligibility Criteria
Optic neuritis patients with complete medical records in multicenter from China.
You may qualify if:
- Clinical diagnosis of optic neuritis
- The patients' medical records were complete
You may not qualify if:
- Patients with unclear diagnosis of optic neuritis
- Incomplete medical records
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Chinese PLA General Hospital
Beijing, Beijing Municipality, 100835, China
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Shihui Wei, M.D
Ophthalmology, the Chinese PLA General Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
February 4, 2020
First Posted
February 6, 2020
Study Start
May 1, 2020
Primary Completion
December 3, 2020
Study Completion
June 30, 2021
Last Updated
January 20, 2021
Record last verified: 2021-01