Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

8.3%

5 terminated out of 60 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

13%

8 trials in Phase 3/4

Results Transparency

17%

5 of 30 completed with results

Key Signals

5 with results86% success

Data Visualizations

Phase Distribution

40Total
Not Applicable (12)
Early P 1 (2)
P 1 (2)
P 2 (16)
P 3 (6)
P 4 (2)

Trial Status

Completed30
Unknown13
Recruiting8
Terminated5
Active Not Recruiting2
Not Yet Recruiting1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 30 completed trials

Clinical Trials (60)

Showing 20 of 20 trials
NCT07100990Phase 3RecruitingPrimary

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

NCT04289909Not ApplicableCompleted

Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)

NCT02521311Phase 2RecruitingPrimary

Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

NCT01623076Active Not Recruiting

The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

NCT02976766Phase 2TerminatedPrimary

Gypenosides Treatment for Optic Neuritis

NCT03651362CompletedPrimary

Linking Optic Nerve MRI and the Retinal Axonal Loss After Optic Neuritis

NCT06453694Phase 2RecruitingPrimary

Efgartigimod for the Treatment of Acute Optic Neuritis

NCT00445367Active Not Recruiting

Biobank For MS And Other Demyelinating Diseases

NCT04762017Phase 2CompletedPrimary

OCS-05 in Patients With Optic Neuritis

NCT06390579Completed

Building Research With Artificial Intelligence in Neuro-Ophthalmology

NCT05487989RecruitingPrimary

VIsual Pathways Model in Neuro-inflammatory Disorders

NCT03963310CompletedPrimary

Optical Coherence Tomography and Optic Neuritis Not Related to Multiple Sclerosis

NCT03401879Not ApplicableRecruiting

Retinal Neuro-vascular Coupling in Patients With Multiple Sclerosis

NCT06916182Not Yet RecruitingPrimary

Evaluation of Optic Neuritis Using Synthetic Quantitative MRI

NCT05540262Not ApplicableRecruitingPrimary

Edaravone in the Treatment of Optic Neuritis

NCT05017142RecruitingPrimary

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

NCT06389968Not ApplicableRecruiting

Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple Sclerosis

NCT03302585Phase 2TerminatedPrimary

High-Dose Vitamin D Induction in Optic Neuritis

NCT03451955Not ApplicableCompletedPrimary

The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CIS

NCT04131764Terminated

Diagnosis of ON With or Without MS or NMOSD

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