NCT04255966

Brief Summary

The aim of this observational study is to collect clinical and radiological results of the new Plasmafit® Revision Structan® Hip Endoprosthesis Cup in a standard patient population and when used in routine clinical practice.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
13mo left

Started Apr 2021

Longer than P75 for all trials

Geographic Reach
1 country

4 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress83%
Apr 2021Jun 2027

First Submitted

Initial submission to the registry

January 30, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 5, 2020

Completed
1.2 years until next milestone

Study Start

First participant enrolled

April 12, 2021

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 16, 2023

Completed
3.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2027

Expected
Last Updated

May 6, 2026

Status Verified

April 1, 2026

Enrollment Period

2.3 years

First QC Date

January 30, 2020

Last Update Submit

April 30, 2026

Conditions

Keywords

Revision of the acetabular implantorthopaedic surgeryosteolysiswear particlescup looseningmalpositioned cup

Outcome Measures

Primary Outcomes (1)

  • Harris Hip Score (Functional results of the operated hip) over time

    The functional results of the operated hip will be assessed with the Harris Hip Score (HHS) and evaluated over time

    up to five years postoperatively

Secondary Outcomes (8)

  • Survival of the implant

    up to five years postoperatively

  • Quality of Life over time

    up to five years postoperatively

  • Radiological Assessment: Osseointegration of the cup over time

    at 3 months, 24 months, 5 years follow-up

  • Radiological assessment: Radiographic loosening of the cup over time

    at 3 months, 24 months, 5 years follow-up

  • Technical problems during surgery

    Intraoperative

  • +3 more secondary outcomes

Study Arms (1)

Plasmafit® Revision Structan®

Plasmafit® Revision Structan® Hip Endoprosthesis Cup

Device: Plasmafit® Revision Structan®

Interventions

Plasmafit® Revision Structan® Hip Endoprosthesis Cup

Plasmafit® Revision Structan®

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients having acute disorders of the hip, requiring primary or revision surgery, which cannot be treated by other therapies: * Degenerative osteoarthritis * Rheumatic arthritis * Fractures of the joint * Femoral head necrosis * Revision surgery where a sufficient intraoperative press-fit can be achieved

You may qualify if:

  • Indication for the cementless Plasmafit® Revision Structan® Hip Endoprosthesis Cup (primary and revision cases, with bone conditions typically demanding a press-fit revision cup)
  • Written informed consent
  • Cases where a press-fit cup fixation is possible

You may not qualify if:

  • Patients \< 18 years
  • Pregnant patients
  • Patients not able to comply with the study demands, i.e. follow-up visits (mentally or physically)
  • Patient has an infection in the hip joint region

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Orthopädische Klinik König-Ludwig-Haus

Würzburg, Bavaria, 97074, Germany

Location

Herzogin Elisabeth Hospital

Braunschweig, Niedersachse, 38124, Germany

Location

Gemeinschaftskrankenhaus Bonn

Bonn, North Rhine-Westphalia, 53113, Germany

Location

Universitätsklinikum des Saarlandes

Homburg, Saarland, 66421, Germany

Location

MeSH Terms

Conditions

OsteolysisJoint DiseasesRheumatic FeverHip FracturesFemur Head NecrosisProsthesis Failure

Condition Hierarchy (Ancestors)

Bone ResorptionBone DiseasesMusculoskeletal DiseasesStreptococcal InfectionsGram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfectionsArthritisRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesFemoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg InjuriesOsteonecrosisNecrosisPathologic ProcessesPathological Conditions, Signs and SymptomsPostoperative Complications

Study Officials

  • Stefan Landgraeber, Prof. Dr.

    University Hospital, Saarland

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 30, 2020

First Posted

February 5, 2020

Study Start

April 12, 2021

Primary Completion

August 16, 2023

Study Completion (Estimated)

June 1, 2027

Last Updated

May 6, 2026

Record last verified: 2026-04

Locations