Chinese Multi-provincial Cohort Study-Beijing Project
CMCS-Beijing
1 other identifier
observational
3,000
1 country
3
Brief Summary
The Chinese Multi-provincial Cohort Study (CMCS)-Beijing project is a sub-study in CMCS participants from Beijing, which intended to investigate the progression and determinants of atherosclerosis and aging related health problems through repeat examinations. Exam 0 to Exam 3 have been conducted during 1992 to 2012. Exam 4 is scheduled in 2020.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2020
Shorter than P25 for all trials
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 22, 2020
CompletedFirst Posted
Study publicly available on registry
February 5, 2020
CompletedStudy Start
First participant enrolled
September 7, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2021
CompletedDecember 4, 2020
December 1, 2020
6 months
January 22, 2020
December 2, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
All fatal and nonfatal acute coronary and stroke events
Acute coronary heart disease events included acute myocardial infarction, sudden death, and other coronary deaths. Acute stroke events included subarachnoid hemorrhage, intracerebral hemorrhage, or cerebral infarction.
From date of enrollment until the date of first documented event or date of cardiovascular death, whichever came first, assessed at least 5 years
Secondary Outcomes (6)
New-onset of coronary events
From date of enrollment until the date of first documented event or date of CHD death, whichever came first, assessed at least 5 years
New-onset of stroke
From date of enrollment until the date of first documented event or date of stroke death, whichever came first, assessed at least 5 years
Total death
From date of enrollment until date of death from all cause, assessed at least 5 years
Cognitive dysfunction
From date of enrollment until date of first documented event, assessed at least 5 years
Olfactory Disorders
From date of enrollment until date of first documented event, assessed at least 5 years
- +1 more secondary outcomes
Interventions
Different level of cardiovascular risk factors, such as aging, hypertension, diabetes, dyslipidemia, smoke, alcohol drink, obesity and et al, associated with genetics, environments and lifestyles
Aging related health problems
Eligibility Criteria
Study participants were recruited from the Chinese Multi-provincial Cohort Study-Beijing Project
You may qualify if:
- Participants from CMCS-Beijing
- sign the informed consent
You may not qualify if:
- participanting in clinical trials
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (3)
Beijing Sijiqing Hospital, Beijing
Beijing, China
Peking University Hospital, Beijing
Beijing, China
Peking University Shougang Hospital
Beijing, China
Biospecimen
Serum, plasma, blood cell and urine
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jing Liu, MD, PhD
Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 22, 2020
First Posted
February 5, 2020
Study Start
September 7, 2020
Primary Completion
March 1, 2021
Study Completion
March 1, 2021
Last Updated
December 4, 2020
Record last verified: 2020-12