Ultrasound-guided Deep and Superficial Serratus Anterior Plane Block
Comparison of Intraoperative Opioid Consumption, Emergence Time and Hemodynamic Stability Between Ultrasound-guided Deep and Superficial Serratus Anterior Plane Block During Video-assisted Thoracoscopic Lobectomy
1 other identifier
interventional
56
1 country
1
Brief Summary
This study evaluates the difference of deep and superficial serratus anterior plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jul 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 15, 2019
CompletedFirst Submitted
Initial submission to the registry
January 31, 2020
CompletedFirst Posted
Study publicly available on registry
February 5, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 29, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
March 31, 2020
CompletedFebruary 5, 2020
February 1, 2020
8 months
January 31, 2020
February 1, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Intraoperative remifentanil consumption
Intraoperative remifentanil consumption will be checked.
through study completion, an average of 1 year
Secondary Outcomes (5)
Emergence time
through study completion, an average of 1 year
Systolic blood pressure
through study completion, an average of 1 year
Heart rate (HR) Heart rate
through study completion, an average of 1 year
Dose of rescue drugs used to control blood pressure and HR
through study completion, an average of 1 year
Postoperative pain: numeric rating scale
30 minutes later operation
Study Arms (2)
Deep Serratus Anterior Plane Block
EXPERIMENTALDeep Serratus Anterior Plane Block was performed just before the start of surgery after anesthetic induction through ultrasound-guidance. 20ml of 0.375% ropivacaine was slowly injected between the fascia of serratus anterior and external intercostal muscle near 5th rib.
Superficial Serratus Anterior Plane Block
ACTIVE COMPARATORSuperficial Serratus Anterior Plane Block was performed just before the start of surgery after anesthetic induction through ultrasound-guidance. 20ml of 0.375% ropivacaine was slowly injected between the fascia of serratus anterior and latissimus dorsi near 5th rib.
Interventions
Deep Serratus Anterior Plane Block was performed just before the start of surgery after anesthetic induction through ultrasound-guidance.
Superficial Serratus Anterior Plane Block was performed just before the start of surgery after anesthetic induction through ultrasound-guidance.
Eligibility Criteria
You may qualify if:
- a) American Society of Anesthesiologists (ASA) physical status 1 or 2
- b) age 20-75 years
- c) elective three port Video-assisted thoracoscopic surgery (VATS) lobectomy.
You may not qualify if:
- a) a history of drug allergy for opioids or local anesthetics
- b) local infection at the injection site and systemic infection
- c) coagulopathy
- d) difficulty in understanding the study protocol
- e) refusal to participate
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Kyungpook national university hospital
Daegu, 700-412, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Saeyoung Kim
Kyungpook National University Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate professor
Study Record Dates
First Submitted
January 31, 2020
First Posted
February 5, 2020
Study Start
July 15, 2019
Primary Completion
February 29, 2020
Study Completion
March 31, 2020
Last Updated
February 5, 2020
Record last verified: 2020-02