NCT04248374

Brief Summary

We are trying to figure out whether the fatty acid taste is differentiated from sour taste.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 7, 2019

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 23, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 30, 2020

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 8, 2020

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2020

Completed
Last Updated

May 7, 2024

Status Verified

May 1, 2024

Enrollment Period

11 months

First QC Date

January 23, 2020

Last Update Submit

May 6, 2024

Conditions

Taste, Altered

Outcome Measures

Primary Outcomes (1)

  • Taste Intensity

    two sets of taste intensity ratings without (Test A) or with (Test B) sour taste adaptation. For test A, participants will taste one of the eight solutions or one of solid fatty acids, and rate its intensity before and after expectorating it.

    4 hours

Study Arms (2)

Fatty Acid Taste

NO INTERVENTION

Fatty acid taste without sour adaptation

Fatty Acid Taste after sour adaptation

EXPERIMENTAL

Fatty Acid Taste after sour adaptation

Other: Taste Intensity

Interventions

Taste IntensityOTHER

Taste intensity with and without sour adaptation

Fatty Acid Taste after sour adaptation

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may not qualify if:

  • taste disorder no allergy to alcohol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Purdue University

West Lafayette, Indiana, 47907, United States

Location

MeSH Terms

Conditions

Dysgeusia

Condition Hierarchy (Ancestors)

Taste DisordersSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Richard D Mattes, PhD

    Purdue University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
three random number and covered sample cup\[
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Model Details: Fatty Acid taste with and without sour adaptation
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Distinguished Professor

Study Record Dates

First Submitted

January 23, 2020

First Posted

January 30, 2020

Study Start

October 7, 2019

Primary Completion

September 8, 2020

Study Completion

December 30, 2020

Last Updated

May 7, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations

US(1)