Taste Function and Eating Habits in Polycystic Ovary Syndrome

NCT04238078 | Completed

• 1 other identifier: 17697
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates taste function and eating habits in patients with PCOS compared to healthy women and before and after oral contraceptive use.

Conditions

Polycystic Ovary Syndrome

Outcome Measures

Primary Outcomes (1)

• Taste function

  Taste function assessed by use of taste strip test

  Three months

Secondary Outcomes (1)

• Eating habits

  Three months

Study Arms (2)

Polycystic ovary syndrome

Women with PCOS diagnosed according to Rotterdam criteria

Drug: Contraceptive

Healthy control

Healthy women without any feature of ovulatory dysfunction or androgen excess

Interventions

Contraceptive DRUG

Oral contraceptive pill

Also known as: birth control pill

Polycystic ovary syndrome

Eligibility Criteria

• Age: 18 Years - 35 Years
• Gender Eligibility Details: Women with PCOS
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Outpatient clinic

You may qualify if:

• Women diagnosed with PCOS (Rotterdam criteria) who will receive oral contraceptive pill for long-term management

You may not qualify if:

• Any systemic illness
• Any other medication use
• Age\<18 or \>35 years
• Pregnant or nursing
• Untreated hypothyroidism or hyperthyroidism
• Known rhinoplasty or nasal surgery
• Known defect in smell or taste function
• Being active smoker.

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University School of Medicine

Ankara, 06100, Turkey (Türkiye)

Location

Related Publications (2)

• Simchen U, Koebnick C, Hoyer S, Issanchou S, Zunft HJ. Odour and taste sensitivity is associated with body weight and extent of misreporting of body weight. Eur J Clin Nutr. 2006 Jun;60(6):698-705. doi: 10.1038/sj.ejcn.1602371. Epub 2006 Jan 25.

  PMID: 16435003 RESULT

• Wolf A, Varga L, Wittibschlager L, Renner B, Mueller CA. A self-administered test of taste function using "Taste Strips". Int Forum Allergy Rhinol. 2016 Apr;6(4):362-6. doi: 10.1002/alr.21681. Epub 2015 Dec 3.

  PMID: 26633243 RESULT

Biospecimen

Retention: SAMPLES WITHOUT DNA

Serum

MeSH Terms

Conditions

Polycystic Ovary Syndrome

Interventions

Contraceptive Agents; Contraceptives, Oral

Condition Hierarchy (Ancestors)

Ovarian Cysts; Cysts; Neoplasms; Ovarian Diseases; Adnexal Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Gonadal Disorders; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Reproductive Control Agents; Physiological Effects of Drugs; Pharmacologic Actions; Chemical Actions and Uses; Therapeutic Uses; Contraceptive Agents, Female

Study Officials

• Bulent Yildiz

  Hacettepe University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Medicine

Study Record Dates

• First Submitted: January 19, 2020
• First Posted: January 23, 2020
• Study Start: January 15, 2020
• Primary Completion: July 15, 2020
• Study Completion: July 15, 2020
• Last Updated: June 30, 2021

Record last verified: 2021-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)