NCT04227067

Brief Summary

In this study we will see if application of TENS for a period of 30 minutes in addition to ibuprofen reduces the pain of emergency department patients with back pain compared with ibuprofen and a sham TENS unit.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 10, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 13, 2020

Completed
7 days until next milestone

Study Start

First participant enrolled

January 20, 2020

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 12, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 12, 2024

Completed
Last Updated

February 13, 2024

Status Verified

February 1, 2024

Enrollment Period

4.1 years

First QC Date

January 10, 2020

Last Update Submit

February 12, 2024

Conditions

Keywords

TENS, back pain, ibuprofen

Outcome Measures

Primary Outcomes (1)

  • Pain severity

    Pain severity graded on a verbal numeric pain scales from none (0) to most (10)

    30 minutes after application of TENS unit

Secondary Outcomes (1)

  • Use of rescue medications

    30 minutes after application of the TENS unit

Study Arms (2)

TENS

ACTIVE COMPARATOR

A TENS device consists of an electric pulse generator and pads that are attached to the skin on around the area of maximal pain. We will use the conventional mode, which provides nerve stimulation with a pulse width of 60 microseconds and a pulse rate of 60 pulses per second. The channel intensity will be gradually increased until the intensity is noticeable but not painful.

Device: TENS

SHAM TENS

SHAM COMPARATOR

In the SHAM TENS group the TENS pads will be attached to the pulse generator and the patients skin around the painful area. The investigator will turn the knobs on but the batteries will be removed from the device.

Device: SHAM TENS

Interventions

TENSDEVICE

An electrical impulse is delivered to the skin around the painful area using pads attached to an electric generator.

TENS
SHAM TENSDEVICE

A TENS generator without batteries is used. The pads are attached to the generator and to the skin around the painful area.

SHAM TENS

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults age 18 years or greater
  • Able to consent
  • Back pain of less than 2 weeks duration
  • Pain severity of at least 5/10 on a verbal numeric scale from 0 (none) to 10 (worst)

You may not qualify if:

  • Pregnant patients
  • Minors
  • Prisoners
  • Neurological deficits

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stony Brook University Hospital

Stony Brook, New York, 11794, United States

Location

Related Publications (1)

  • Otterness K, McMahon B, Ma M, Thode HC Jr, Singer AJ. The use of TENS for the treatment of back pain in the emergency department: A randomized controlled trial. Acad Emerg Med. 2025 Aug;32(8):828-835. doi: 10.1111/acem.70013. Epub 2025 Apr 9.

MeSH Terms

Conditions

Back Pain

Interventions

Transcutaneous Electric Nerve Stimulation

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsPhysical Therapy ModalitiesRehabilitationAnalgesiaAnesthesia and Analgesia

Study Officials

  • Adam Singer, MD

    Stony Brook University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor and Vice Chairman for Research

Study Record Dates

First Submitted

January 10, 2020

First Posted

January 13, 2020

Study Start

January 20, 2020

Primary Completion

February 12, 2024

Study Completion

February 12, 2024

Last Updated

February 13, 2024

Record last verified: 2024-02

Locations