NCT04223440

Brief Summary

The project aims to evaluate the contribution of texture analysis on MRI sections, and the technical feasibility, reproducibility, and clinical relevance of quantitative ultrasound and elastography to characterize the composition and volume of infraspinatus muscle in postero-superior rotator cuff tears. The perspectives are to optimize the imaging to allow a quantitative, objective and reproducible analysis of the muscle tissue and its characteristics.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 6, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 10, 2020

Completed
11 months until next milestone

Study Start

First participant enrolled

November 24, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 19, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 19, 2021

Completed
Last Updated

February 13, 2026

Status Verified

February 1, 2026

Enrollment Period

4 months

First QC Date

January 6, 2020

Last Update Submit

February 10, 2026

Conditions

Keywords

Rotator Cuff TearsMRIUltrasonographic explorations

Outcome Measures

Primary Outcomes (1)

  • MRI Texture Index (MTI)

    MRI texture index (MTI) on the healthy side and pathological side

    up to 2 months

Secondary Outcomes (2)

  • Ultrasound Texture Index (UTI)

    up to 2 months

  • velocity of shear wave in m.s-1

    up to 2 months

Study Arms (2)

Postero-superior Rotator Cuff Tear

EXPERIMENTAL

MRI, ultrasonographic explorations

Other: MRIOther: ultrasonographic explorations

Healthy Postero-superior Rotator Cuff

OTHER

MRI, ultrasonographic explorations

Other: MRIOther: ultrasonographic explorations

Interventions

MRIOTHER

MRI on both shoulder

Healthy Postero-superior Rotator CuffPostero-superior Rotator Cuff Tear

ultrasound and elastography explorations on both shoulder

Healthy Postero-superior Rotator CuffPostero-superior Rotator Cuff Tear

Eligibility Criteria

Age35 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • ≥ 35 years-old and ≤75 years-old
  • tendonous, transfixing, postero-superior, unilateral and symptomatic rotator cuff lesions
  • controlateral shoulder without symptom, without rotator cuff injuries, without medical ou surgical history
  • written informed consent
  • affiliation to a social security system

You may not qualify if:

  • pregnant woman
  • patient under legal protection
  • contraindications to MRI
  • traumatic or surgical or medical relevant history on shoulder
  • general or local disease affecting the skeletal striated muscle

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chu Tours

Tours, 37044, France

Location

MeSH Terms

Conditions

Rotator Cuff Injuries

Condition Hierarchy (Ancestors)

RuptureWounds and InjuriesShoulder InjuriesTendon Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 6, 2020

First Posted

January 10, 2020

Study Start

November 24, 2020

Primary Completion

March 19, 2021

Study Completion

March 19, 2021

Last Updated

February 13, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations