NCT04208750

Brief Summary

Randomized, bilateral, cross-over dispensing study of a standard and VR800 refraction and associated spectacle lenses.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
119

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Nov 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 14, 2019

Completed
4 days until next milestone

Study Start

First participant enrolled

November 18, 2019

Completed
1 month until next milestone

First Posted

Study publicly available on registry

December 23, 2019

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2021

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

March 14, 2022

Completed
Last Updated

March 14, 2022

Status Verified

February 1, 2022

Enrollment Period

1.2 years

First QC Date

November 14, 2019

Results QC Date

January 6, 2022

Last Update Submit

February 16, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Subjective Questionnaire Response

    Patient questions of refraction preference for quickness, efficiency, comfort, and stress

    at Visit 5 (final visit), up to 5 weeks

Study Arms (2)

R-Refraction

EXPERIMENTAL
Device: Vision R-800 PhoropterDevice: Standard Phoropter

S-Refraction

ACTIVE COMPARATOR
Device: Vision R-800 PhoropterDevice: Standard Phoropter

Interventions

Refraction utilizing the Vision R-800 Phoropter with resulting glasses

R-RefractionS-Refraction

Refraction utilizing the standard phoropter with resulting glasses

R-RefractionS-Refraction

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • current adaptated progressive addition lens wearer, if bifocal lens required
  • wearable pair of glasses \< 2 years old
  • wear glasses at least 6 hours per day

You may not qualify if:

  • Eye Disease with an impact on visual acuity or binocular vision abnormalities (by self-report)
  • Formal training in optometry, vision science or in the eyecare field

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Indiana University Clinical Optics Research Lab

Bloomington, Indiana, 47405, United States

Location

MeSH Terms

Conditions

MyopiaHyperopiaAstigmatismPresbyopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Limitations and Caveats

Due to the COVID-19 pandemic this study was interrupted. Therefore, obtaining complete in-office data for some subjects was not possible. However, for all subjects possible at-home data was still obtained, as well as any in-office data that could be obtained remotely. Under allowed protocol deviation, some data was also collected in July following re-opening of the lab. We did rule out an effect of in-office as compared to remote data due to the COVID-19 pandemic.

Results Point of Contact

Title
Dr. Dawn Meyer
Organization
Indiana University

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor, Associate Dean for Research, and Director of the Borish Center for Ophthalmic Research

Study Record Dates

First Submitted

November 14, 2019

First Posted

December 23, 2019

Study Start

November 18, 2019

Primary Completion

February 1, 2021

Study Completion

February 1, 2021

Last Updated

March 14, 2022

Results First Posted

March 14, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share

Locations