Effects of Recruitment Maneuver on Functional Residual Capacity

NCT04208737 | Completed

• 1 other identifier: 2018/938
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 2

Brief Summary

Recruitment maneuver is frequently used in daily anaesthesia routine to prevent athelectasia and ventilation perfusion mismatch. Especially pneumoperitoneum in laparoscopic surgeries affects the functional residual capacity (FRC) negatively. Recently, FRC can be measured at bedside in intensive care units. The lack of studies evaluating FRC measurements peroperatively and how recruitment maneuvers affect it, attract attention.

Conditions

Anesthesia; Surgery; Atelectasis

Outcome Measures

Primary Outcomes (1)

• Comparison of FRC measurements at beginning and end of anesthesia

  First FRC will be measured after ; the last FRC will be measure bedore the extubation

  within max 5 minutes after the intubation and with max 5 minutes before the extubation

Secondary Outcomes (1)

• Positive room air test

  in recovery room 30 minutes after operation

Study Arms (2)

control group

NO INTERVENTION

3 FRC measurements will be perforemed, whereby : First measurement; after aneshesia induction and intubation. Second measurement; after pneumoperitoneum Third measurement; end of the operation After the operation,Postoperative Room Air Test (RAT) will be applied.

study group

EXPERIMENTAL

5 FRC measurements will be performed We will apply recruitment maneuver two times to patients with 30cmH2O pressure for 15 seconds . First Recruitment maneuver will be applied after the fşrst measurement of FRC following intubation Second Recuitment maneuver will be applied at the end of operation First FRC measurement after anesthesia induction and intubation. Second FRC measurement after first recruitment maneuver Third FRC measurement; after pneumoperitoneum Fourth FRC measurement before second recruitment maneuver Fifth FRC measurement after second recruitment maneuver and at the end of operation

Procedure: recruitment maneuver

Interventions

recruitment maneuver PROCEDURE

30 cmH2O pressure 15 seconds

study group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years age 2-no lung disease 3-laparoscopic cholecystectomies surgery

You may not qualify if:

• \<18 years old
• \>65 years old
• denial of patient
• patients having one of: lung disease, cardiac failure, severe cardiac valvular disease

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (2)

Istanbul University

Istanbul, 34069, Turkey (Türkiye)

Location

Istanbul University, Department of Anesthesiology

Istanbul, 34093, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pulmonary Atelectasis

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases

Study Officials

• Elif Aygun, MD

  Istanbul University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof.Dr.

Study Record Dates

• First Submitted: December 16, 2019
• First Posted: December 23, 2019
• Study Start: December 23, 2019
• Primary Completion: May 1, 2020
• Study Completion: June 1, 2020
• Last Updated: June 9, 2020

Record last verified: 2020-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (2)